Wnt5a Signaling in Cancer

Wnt5a Signaling in Cancer

Wnt5a is involved in activating several non-canonical WNT signaling pathways, through binding to different members of the Frizzled- and Ror-family receptors. Wnt5a signaling is critical for regulating normal developmental processes, including proliferation, differentiation, migration, adhesion and p...

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Bibliographic Details
Main Authors: Marwa S. Asem, Steven Buechler, Rebecca Burkhalter Wates, Daniel L. Miller, M. Sharon Stack
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Cancers
Subjects:
Wnt5a
non-canonical Wnt signaling
frizzled (Fzd)
receptor tyrosine kinase-like orphan receptor (Ror)
cancer
ovarian cancer
senescence
inflammation
microenvironment
epithelial-mesenchymal transition (EMT)
Online Access:http://www.mdpi.com/2072-6694/8/9/79

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