Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study

Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study

Extensive in vitro studies have been conducted to evaluate the anticancer activity of oral hypoglycemic agents. Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media consisting of extremely high concentrations of growth f...

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Bibliographic Details
Main Authors: Bardaweel Sanaa K., Alsalamat Husam A., Aleidi Shereen M., Bashatwah Rasha M.
Format: Article
Language:English
Published: Sciendo 2018-12-01
Series:Acta Pharmaceutica
Subjects:
biguanide
breast cancer
apoptosis
glucose
ampk
Online Access:https://doi.org/10.2478/acph-2018-0031

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