Polymorphisms associated with type 1 diabetes mellitus

Polymorphisms associated with type 1 diabetes mellitus

Background Type 1 diabetes mellitus (T1DM) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of pancreatic islets. The genetic factors involved consist of at least five vulnerability genes:  HLA, INS, CTLA-4, PTPN22, and IL2RA/CD25. Objective To investigate for...

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Bibliographic Details
Main Authors: Rachman Indra Jaya, Yenni Riska Zettyana, Achirul Bakri, Yuwono Yuwono, Aditiawati Aditiawati
Format: Article
Language:English
Published: Indonesian Pediatric Society Publishing House 2018-12-01
Series:Paediatrica Indonesiana
Subjects:
T1DM; PTPN22-1123 G>C; CTLA-4 49A/G; PCR-RFLP; polymorphism
Online Access:https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1894

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