The role of TRP proteins in mast cells

The role of TRP proteins in mast cells

TRP proteins form cation channels that are regulated through strikingly diverse mechanisms including multiple cell surface receptors, changes in temperature, in pH and osmolarity, in cytosolic Ca2+ concentration ([Ca2+]i) and by phosphoinositides. The 28 TRP proteins identified in mammals are classi...

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Bibliographic Details
Main Authors: Marc eFreichel, Julia eAlmering, Volodymyr eTsvilovskyy
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Immunology
Subjects:
Ca2+ signaling
mast cell activation
TRP proteins
cation channels
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00150/full

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