Prosthetic valve thrombosis management in a patient with deranged coagulation parameters
Appropriate guidelines are not available at present for the management of patient with acute prosthetic heart valve thrombosis presenting with New York Heart Association Class IV symptoms and having deranged coagulation profile. Here, we thrombolyzed one such patient with tissue plasminogen activato...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of the Practice of Cardiovascular Sciences |
| Subjects: | |
| Online Access: | http://www.j-pcs.org/article.asp?issn=2395-5414;year=2018;volume=4;issue=3;spage=244;epage=246;aulast=Parashar |
| _version_ | 1819320169461186560 |
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| author | Nitin Kumar Parashar Mumun Sinha Shanmugam Krishnan Sandeep Seth |
| author_facet | Nitin Kumar Parashar Mumun Sinha Shanmugam Krishnan Sandeep Seth |
| author_sort | Nitin Kumar Parashar |
| collection | DOAJ |
| description | Appropriate guidelines are not available at present for the management of patient with acute prosthetic heart valve thrombosis presenting with New York Heart Association Class IV symptoms and having deranged coagulation profile. Here, we thrombolyzed one such patient with tissue plasminogen activator (alteplase) using very slow infusion (25 mg over 24 h) which resulted in rapid improvement in symptoms and subsequent resolution of pulmonary edema with simultaneous improvement of echocardiographic gradient and fluoroscopic movement of leaflets. |
| first_indexed | 2024-12-24T11:15:18Z |
| format | Article |
| id | doaj.art-e785ff2eb7ae4185a3d8ca56fbaf70f6 |
| institution | Directory Open Access Journal |
| issn | 2395-5414 2454-2830 |
| language | English |
| last_indexed | 2024-12-24T11:15:18Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Practice of Cardiovascular Sciences |
| spelling | doaj.art-e785ff2eb7ae4185a3d8ca56fbaf70f62022-12-21T16:58:24ZengWolters Kluwer Medknow PublicationsJournal of the Practice of Cardiovascular Sciences2395-54142454-28302018-01-014324424610.4103/jpcs.jpcs_42_18Prosthetic valve thrombosis management in a patient with deranged coagulation parametersNitin Kumar ParasharMumun SinhaShanmugam KrishnanSandeep SethAppropriate guidelines are not available at present for the management of patient with acute prosthetic heart valve thrombosis presenting with New York Heart Association Class IV symptoms and having deranged coagulation profile. Here, we thrombolyzed one such patient with tissue plasminogen activator (alteplase) using very slow infusion (25 mg over 24 h) which resulted in rapid improvement in symptoms and subsequent resolution of pulmonary edema with simultaneous improvement of echocardiographic gradient and fluoroscopic movement of leaflets.http://www.j-pcs.org/article.asp?issn=2395-5414;year=2018;volume=4;issue=3;spage=244;epage=246;aulast=ParasharDeranged coagulation parametersprosthetic heart valve thrombosisthrombolysis |
| spellingShingle | Nitin Kumar Parashar Mumun Sinha Shanmugam Krishnan Sandeep Seth Prosthetic valve thrombosis management in a patient with deranged coagulation parameters Journal of the Practice of Cardiovascular Sciences Deranged coagulation parameters prosthetic heart valve thrombosis thrombolysis |
| title | Prosthetic valve thrombosis management in a patient with deranged coagulation parameters |
| title_full | Prosthetic valve thrombosis management in a patient with deranged coagulation parameters |
| title_fullStr | Prosthetic valve thrombosis management in a patient with deranged coagulation parameters |
| title_full_unstemmed | Prosthetic valve thrombosis management in a patient with deranged coagulation parameters |
| title_short | Prosthetic valve thrombosis management in a patient with deranged coagulation parameters |
| title_sort | prosthetic valve thrombosis management in a patient with deranged coagulation parameters |
| topic | Deranged coagulation parameters prosthetic heart valve thrombosis thrombolysis |
| url | http://www.j-pcs.org/article.asp?issn=2395-5414;year=2018;volume=4;issue=3;spage=244;epage=246;aulast=Parashar |
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