A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue

Introduction: Various materials have been used in tympanoplasty to ensure the adherence of the graft with the remnant tympanic membrane. This study aims to compare the clinical outcomes of type I tympanoplasty done with and without fibrin glue. Materials and Methods:           This is a pr...

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Main Authors: Somu Lakshmanan, Preethi Umamaheswaran
Format: Article
Language:English
Published: The Association of Otolaryngologists of India, West Bengal 2019-04-01
Series:Bengal Journal of Otolaryngology and Head Neck Surgery
Subjects:
Online Access:https://bjohns.in/journal3/index.php/bjohns/article/view/220
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author Somu Lakshmanan
Preethi Umamaheswaran
author_facet Somu Lakshmanan
Preethi Umamaheswaran
author_sort Somu Lakshmanan
collection DOAJ
description Introduction: Various materials have been used in tympanoplasty to ensure the adherence of the graft with the remnant tympanic membrane. This study aims to compare the clinical outcomes of type I tympanoplasty done with and without fibrin glue. Materials and Methods:           This is a prospective comparative study conducted in a tertiary care centre between August 2014 and July 2016. A sample size of 70 patients was used. The patients were randomly divided into two groups – Group A and Group B. Patients in group A underwent tympanoplasty with fibrin glue and patients in group B underwent tympanoplasty without fibrin glue. The patients were followed up for 6 months and the postoperative hearing improvement and graft uptake rates were compared. Results: The pre-operative mean pure tone average for group A was 34.33±7.3dB; it improved to 22.14±6.5 at the end of 6 months. In group B, it improved from 34.25±8dB to 22.64±7.4dB at the end of 6 months. There was no statistical significance in hearing improvement between both the groups. Though there was no statistically significant difference in the graft uptake rates between group A (94.3%) and group B (91.4%), fibrin glue had better outcomes with larger perforations. Conclusion: The use of fibrin glue in tympanoplasty is safe and it has a particular advantage in the graft uptake in subtotal perforations.
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spelling doaj.art-e78f3ceb606b4aaea943e04876ddea442024-04-03T10:41:02ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-24072019-04-0127110.47210/bjohns.2019.v27i1.220A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin GlueSomu Lakshmanan0Preethi Umamaheswaran1Sri Ramachandra Institute of Higher Education and Research Porur, Chennai -600011Apollo Specialty Hospital, ChennaiIntroduction: Various materials have been used in tympanoplasty to ensure the adherence of the graft with the remnant tympanic membrane. This study aims to compare the clinical outcomes of type I tympanoplasty done with and without fibrin glue. Materials and Methods:           This is a prospective comparative study conducted in a tertiary care centre between August 2014 and July 2016. A sample size of 70 patients was used. The patients were randomly divided into two groups – Group A and Group B. Patients in group A underwent tympanoplasty with fibrin glue and patients in group B underwent tympanoplasty without fibrin glue. The patients were followed up for 6 months and the postoperative hearing improvement and graft uptake rates were compared. Results: The pre-operative mean pure tone average for group A was 34.33±7.3dB; it improved to 22.14±6.5 at the end of 6 months. In group B, it improved from 34.25±8dB to 22.64±7.4dB at the end of 6 months. There was no statistical significance in hearing improvement between both the groups. Though there was no statistically significant difference in the graft uptake rates between group A (94.3%) and group B (91.4%), fibrin glue had better outcomes with larger perforations. Conclusion: The use of fibrin glue in tympanoplasty is safe and it has a particular advantage in the graft uptake in subtotal perforations.https://bjohns.in/journal3/index.php/bjohns/article/view/220TympanoplastyFibrin Tissue Adhesive
spellingShingle Somu Lakshmanan
Preethi Umamaheswaran
A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue
Bengal Journal of Otolaryngology and Head Neck Surgery
Tympanoplasty
Fibrin Tissue Adhesive
title A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue
title_full A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue
title_fullStr A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue
title_full_unstemmed A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue
title_short A Comparative Study of Outcomes of Type I Tympanoplasty with or without Fibrin Glue
title_sort comparative study of outcomes of type i tympanoplasty with or without fibrin glue
topic Tympanoplasty
Fibrin Tissue Adhesive
url https://bjohns.in/journal3/index.php/bjohns/article/view/220
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AT somulakshmanan comparativestudyofoutcomesoftypeitympanoplastywithorwithoutfibringlue
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