Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study.
To evaluate circadian fluctuations and night/day ratio of Heart Rate Variability (HRV) spectral components in patients with obstructive sleep apnea (OSA) in comparison with controls.This is a simultaneous HRV-polysomnographic (PSG) study including 29 patients with OSA and 18 age-sex-matched controls...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2018-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5843243?pdf=render |
| _version_ | 1818927555030286336 |
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| author | Maria Salsone Basilio Vescio Andrea Quattrone Ferdinando Roccia Miriam Sturniolo Francesco Bono Umberto Aguglia Antonio Gambardella Aldo Quattrone |
| author_facet | Maria Salsone Basilio Vescio Andrea Quattrone Ferdinando Roccia Miriam Sturniolo Francesco Bono Umberto Aguglia Antonio Gambardella Aldo Quattrone |
| author_sort | Maria Salsone |
| collection | DOAJ |
| description | To evaluate circadian fluctuations and night/day ratio of Heart Rate Variability (HRV) spectral components in patients with obstructive sleep apnea (OSA) in comparison with controls.This is a simultaneous HRV-polysomnographic (PSG) study including 29 patients with OSA and 18 age-sex-matched controls. Four patients with OSA dropped out. All participants underwent PSG and HRV analysis. We measured the 24-hour fluctuations and the night/day ratio of low frequency (LF) and high frequency (HF) spectral components of HRV in all subjects and controls. The LF night/day ratio was termed the cardiac sympathetic index while the HF night/day ratio was termed the cardiac parasympathetic index.All twenty-five OSA patients were PSG positive (presence of OSA) while 18 controls were PSG negative (absence of OSA). There was no significant difference in LF and HF 24-hour fluctuation values between OSA patients and controls. In OSA patients, LF and HF values were significantly higher during night-time than day time recordings (p<0.001). HF night/day ratio (cardiac parasympathetic index) accurately (100%) differentiated OSA patients from controls without an overlap of individual values. The LF night/day ratio (cardiac sympathetic index) had sensitivity of 84%, specificity of 72.2% and accuracy of 79.1% in distinguishing between groups.The cardiac parasympathetic index accurately differentiated patients with OSA from controls, on an individual basis. |
| first_indexed | 2024-12-20T03:14:52Z |
| format | Article |
| id | doaj.art-e7986d5e80eb4a588f0ac2755647150b |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T03:14:52Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-e7986d5e80eb4a588f0ac2755647150b2022-12-21T19:55:23ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01133e019387910.1371/journal.pone.0193879Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study.Maria SalsoneBasilio VescioAndrea QuattroneFerdinando RocciaMiriam SturnioloFrancesco BonoUmberto AgugliaAntonio GambardellaAldo QuattroneTo evaluate circadian fluctuations and night/day ratio of Heart Rate Variability (HRV) spectral components in patients with obstructive sleep apnea (OSA) in comparison with controls.This is a simultaneous HRV-polysomnographic (PSG) study including 29 patients with OSA and 18 age-sex-matched controls. Four patients with OSA dropped out. All participants underwent PSG and HRV analysis. We measured the 24-hour fluctuations and the night/day ratio of low frequency (LF) and high frequency (HF) spectral components of HRV in all subjects and controls. The LF night/day ratio was termed the cardiac sympathetic index while the HF night/day ratio was termed the cardiac parasympathetic index.All twenty-five OSA patients were PSG positive (presence of OSA) while 18 controls were PSG negative (absence of OSA). There was no significant difference in LF and HF 24-hour fluctuation values between OSA patients and controls. In OSA patients, LF and HF values were significantly higher during night-time than day time recordings (p<0.001). HF night/day ratio (cardiac parasympathetic index) accurately (100%) differentiated OSA patients from controls without an overlap of individual values. The LF night/day ratio (cardiac sympathetic index) had sensitivity of 84%, specificity of 72.2% and accuracy of 79.1% in distinguishing between groups.The cardiac parasympathetic index accurately differentiated patients with OSA from controls, on an individual basis.http://europepmc.org/articles/PMC5843243?pdf=render |
| spellingShingle | Maria Salsone Basilio Vescio Andrea Quattrone Ferdinando Roccia Miriam Sturniolo Francesco Bono Umberto Aguglia Antonio Gambardella Aldo Quattrone Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study. PLoS ONE |
| title | Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study. |
| title_full | Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study. |
| title_fullStr | Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study. |
| title_full_unstemmed | Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study. |
| title_short | Cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea: A simultaneous polysomnographic-heart rate variability study. |
| title_sort | cardiac parasympathetic index identifies subjects with adult obstructive sleep apnea a simultaneous polysomnographic heart rate variability study |
| url | http://europepmc.org/articles/PMC5843243?pdf=render |
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