Leptin Receptors Are Not Required for Roux-en-Y Gastric Bypass Surgery to Normalize Energy and Glucose Homeostasis in Rats

Leptin Receptors Are Not Required for Roux-en-Y Gastric Bypass Surgery to Normalize Energy and Glucose Homeostasis in Rats

Sensitization to the adipokine leptin is a promising therapeutic strategy against obesity and its comorbidities and has been proposed to contribute to the lasting metabolic benefits of Roux-en-Y gastric bypass (RYGB) surgery. We formally tested this idea using Zucker fatty <i>fa/fa</i> r...

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Bibliographic Details
Main Authors: Mohammed K. Hankir, Laura Rotzinger, Arno Nordbeck, Caroline Corteville, Ulrich Dischinger, Juna-Lisa Knop, Annett Hoffmann, Christoph Otto, Florian Seyfried
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Nutrients
Subjects:
Roux-en-Y gastric bypass surgery
energy homeostasis
glucose homeostasis
fatty liver
leptin system
Zucker fatty <i>fa/fa</i> rats
Online Access:https://www.mdpi.com/2072-6643/13/5/1544

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