Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast

In recent decades, photoacoustic imaging has been used widely in biomedical research, providing molecular and functional information from biological tissues in vivo. In addition to being used for research in small animals, photoacoustic imaging has also been utilized for in vivo human studies, achie...

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Main Authors: Seongyi Han, Haeni Lee, Chulhong Kim, Jeesu Kim
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/5/382
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author Seongyi Han
Haeni Lee
Chulhong Kim
Jeesu Kim
author_facet Seongyi Han
Haeni Lee
Chulhong Kim
Jeesu Kim
author_sort Seongyi Han
collection DOAJ
description In recent decades, photoacoustic imaging has been used widely in biomedical research, providing molecular and functional information from biological tissues in vivo. In addition to being used for research in small animals, photoacoustic imaging has also been utilized for in vivo human studies, achieving a multispectral photoacoustic response in deep tissue. There have been several clinical trials for screening cancer patients by analyzing multispectral responses, which in turn provide metabolomic information about the underlying biological tissues. This review summarizes the methods and results of clinical photoacoustic trials available in the literature to date to classify cancerous tissues, specifically of the thyroid and breast. From the review, we can conclude that a great potential exists for photoacoustic imaging to be used as a complementary modality to improve diagnostic accuracy for suspicious tumors, thus significantly benefitting patients’ healthcare.
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spelling doaj.art-e79a4568e1f84bdbb2e6a14dd464a38f2023-11-23T12:06:35ZengMDPI AGMetabolites2218-19892022-04-0112538210.3390/metabo12050382Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and BreastSeongyi Han0Haeni Lee1Chulhong Kim2Jeesu Kim3Departments of Cogno-Mechatronics Engineering and Optics & Mechatronics Engineering, Pusan National University, Busan 46241, KoreaDepartments of Cogno-Mechatronics Engineering and Optics & Mechatronics Engineering, Pusan National University, Busan 46241, KoreaDepartments of Convergence IT Engineering, Mechanical Engineering, and Electrical Engineering, School of Interdisciplinary Bioscience and Bioengineering, Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang 37673, KoreaDepartments of Cogno-Mechatronics Engineering and Optics & Mechatronics Engineering, Pusan National University, Busan 46241, KoreaIn recent decades, photoacoustic imaging has been used widely in biomedical research, providing molecular and functional information from biological tissues in vivo. In addition to being used for research in small animals, photoacoustic imaging has also been utilized for in vivo human studies, achieving a multispectral photoacoustic response in deep tissue. There have been several clinical trials for screening cancer patients by analyzing multispectral responses, which in turn provide metabolomic information about the underlying biological tissues. This review summarizes the methods and results of clinical photoacoustic trials available in the literature to date to classify cancerous tissues, specifically of the thyroid and breast. From the review, we can conclude that a great potential exists for photoacoustic imaging to be used as a complementary modality to improve diagnostic accuracy for suspicious tumors, thus significantly benefitting patients’ healthcare.https://www.mdpi.com/2218-1989/12/5/382photoacoustic imagingthyroid cancerbreast cancermultispectral analysisclinical imaging
spellingShingle Seongyi Han
Haeni Lee
Chulhong Kim
Jeesu Kim
Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast
Metabolites
photoacoustic imaging
thyroid cancer
breast cancer
multispectral analysis
clinical imaging
title Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast
title_full Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast
title_fullStr Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast
title_full_unstemmed Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast
title_short Review on Multispectral Photoacoustic Analysis of Cancer: Thyroid and Breast
title_sort review on multispectral photoacoustic analysis of cancer thyroid and breast
topic photoacoustic imaging
thyroid cancer
breast cancer
multispectral analysis
clinical imaging
url https://www.mdpi.com/2218-1989/12/5/382
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