Intercellular Protein Transfer from Thymocytes to Thymic Epithelial Cells.

Promiscuous expression of tissue restricted antigens (TRAs) in medullary thymic epithelial cells (mTECs) is crucial for negative selection of self-reactive T cells to establish central tolerance. Intercellular transfer of self-peptide-MHC complexes from mTECs to thymic dendritic cells (DCs) allows D...

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Main Authors: Hong-Xia Wang, Yu-Rong Qiu, Xiao-Ping Zhong
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4811443?pdf=render