Dopey2 and Pcdh7 orchestrate the development of embryonic neural stem cells/ progenitors in zebrafish

Summary: DOPEY2 has been shown to be associated with Down syndrome and PCDH7 might be involved in Rett syndrome and MECP2 duplication syndrome. The mechanism how both proteins play roles in these syndromes are largely unknown. Here, we show that Dopey2 and Pcdh7 balance the proliferation and differe...

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Bibliographic Details
Main Authors: Yue Xiao, Min Hu, Qiyan Lin, Ting Zhang, Siying Li, Linjuan Shu, Xiuli Song, Xiaoyong Xu, Wentong Meng, Xue Li, Hong Xu, Xianming Mo
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003504