Age-related change in contribution of stroke volume to central pulse pressure
We investigated age-related change in the contribution of stroke volume (SV) to central PP (cPP). Eighty seven adult subjects who were free of vasoactive agents were included. Subjects were divided into three age groups: young (20–39 years, n = 26), middle (40–49 years, n = 29), and old (≥50 years,...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2017-04-01
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Series: | Clinical and Experimental Hypertension |
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Online Access: | http://dx.doi.org/10.1080/10641963.2016.1259331 |
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author | Atsushi Nakagomi Sho Okada Nobusada Funabashi Yoshio Kobayashi |
author_facet | Atsushi Nakagomi Sho Okada Nobusada Funabashi Yoshio Kobayashi |
author_sort | Atsushi Nakagomi |
collection | DOAJ |
description | We investigated age-related change in the contribution of stroke volume (SV) to central PP (cPP). Eighty seven adult subjects who were free of vasoactive agents were included. Subjects were divided into three age groups: young (20–39 years, n = 26), middle (40–49 years, n = 29), and old (≥50 years, n = 32). SV was calculated by Doppler echocardiography. Hemodynamic indices were measured using a brachial cuff-based oscillometric method. The brachial and cPP showed a small decline from the young group to the middle group and a greater rise after 50 years old. SV significantly and positively correlated with brachial (r = 0.53, p < 0.01) and cPP (r = 0.57, p < 0.01) in the young group. In the middle group, the association of SV with brachial pulse pressure was significant (r = 0.38, p = 0.04) and that with cPP was bordering significant (r = 0.34, p = 0.07). No significant association was found between SV and PP in the old group. In conclusion, the contribution of SV to cPP decreases with age. Age-related changes in the determinants of cPP should be considered when investigating the clinical value of cPP. |
first_indexed | 2024-03-11T23:46:31Z |
format | Article |
id | doaj.art-e79ebb505a3a4da5bba58f4475e0187b |
institution | Directory Open Access Journal |
issn | 1064-1963 1525-6006 |
language | English |
last_indexed | 2024-03-11T23:46:31Z |
publishDate | 2017-04-01 |
publisher | Taylor & Francis Group |
record_format | Article |
series | Clinical and Experimental Hypertension |
spelling | doaj.art-e79ebb505a3a4da5bba58f4475e0187b2023-09-19T09:24:45ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062017-04-0139328428910.1080/10641963.2016.12593311259331Age-related change in contribution of stroke volume to central pulse pressureAtsushi Nakagomi0Sho Okada1Nobusada Funabashi2Yoshio Kobayashi3Chiba University Graduate School of MedicineChiba University Graduate School of MedicineChiba University Graduate School of MedicineChiba University Graduate School of MedicineWe investigated age-related change in the contribution of stroke volume (SV) to central PP (cPP). Eighty seven adult subjects who were free of vasoactive agents were included. Subjects were divided into three age groups: young (20–39 years, n = 26), middle (40–49 years, n = 29), and old (≥50 years, n = 32). SV was calculated by Doppler echocardiography. Hemodynamic indices were measured using a brachial cuff-based oscillometric method. The brachial and cPP showed a small decline from the young group to the middle group and a greater rise after 50 years old. SV significantly and positively correlated with brachial (r = 0.53, p < 0.01) and cPP (r = 0.57, p < 0.01) in the young group. In the middle group, the association of SV with brachial pulse pressure was significant (r = 0.38, p = 0.04) and that with cPP was bordering significant (r = 0.34, p = 0.07). No significant association was found between SV and PP in the old group. In conclusion, the contribution of SV to cPP decreases with age. Age-related changes in the determinants of cPP should be considered when investigating the clinical value of cPP.http://dx.doi.org/10.1080/10641963.2016.1259331agingcentral blood pressurepulse pressurestroke volume |
spellingShingle | Atsushi Nakagomi Sho Okada Nobusada Funabashi Yoshio Kobayashi Age-related change in contribution of stroke volume to central pulse pressure Clinical and Experimental Hypertension aging central blood pressure pulse pressure stroke volume |
title | Age-related change in contribution of stroke volume to central pulse pressure |
title_full | Age-related change in contribution of stroke volume to central pulse pressure |
title_fullStr | Age-related change in contribution of stroke volume to central pulse pressure |
title_full_unstemmed | Age-related change in contribution of stroke volume to central pulse pressure |
title_short | Age-related change in contribution of stroke volume to central pulse pressure |
title_sort | age related change in contribution of stroke volume to central pulse pressure |
topic | aging central blood pressure pulse pressure stroke volume |
url | http://dx.doi.org/10.1080/10641963.2016.1259331 |
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