Age-related change in contribution of stroke volume to central pulse pressure

We investigated age-related change in the contribution of stroke volume (SV) to central PP (cPP). Eighty seven adult subjects who were free of vasoactive agents were included. Subjects were divided into three age groups: young (20–39 years, n = 26), middle (40–49 years, n = 29), and old (≥50 years,...

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Main Authors: Atsushi Nakagomi, Sho Okada, Nobusada Funabashi, Yoshio Kobayashi
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2016.1259331
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author Atsushi Nakagomi
Sho Okada
Nobusada Funabashi
Yoshio Kobayashi
author_facet Atsushi Nakagomi
Sho Okada
Nobusada Funabashi
Yoshio Kobayashi
author_sort Atsushi Nakagomi
collection DOAJ
description We investigated age-related change in the contribution of stroke volume (SV) to central PP (cPP). Eighty seven adult subjects who were free of vasoactive agents were included. Subjects were divided into three age groups: young (20–39 years, n = 26), middle (40–49 years, n = 29), and old (≥50 years, n = 32). SV was calculated by Doppler echocardiography. Hemodynamic indices were measured using a brachial cuff-based oscillometric method. The brachial and cPP showed a small decline from the young group to the middle group and a greater rise after 50 years old. SV significantly and positively correlated with brachial (r = 0.53, p < 0.01) and cPP (r = 0.57, p < 0.01) in the young group. In the middle group, the association of SV with brachial pulse pressure was significant (r = 0.38, p = 0.04) and that with cPP was bordering significant (r = 0.34, p = 0.07). No significant association was found between SV and PP in the old group. In conclusion, the contribution of SV to cPP decreases with age. Age-related changes in the determinants of cPP should be considered when investigating the clinical value of cPP.
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spelling doaj.art-e79ebb505a3a4da5bba58f4475e0187b2023-09-19T09:24:45ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062017-04-0139328428910.1080/10641963.2016.12593311259331Age-related change in contribution of stroke volume to central pulse pressureAtsushi Nakagomi0Sho Okada1Nobusada Funabashi2Yoshio Kobayashi3Chiba University Graduate School of MedicineChiba University Graduate School of MedicineChiba University Graduate School of MedicineChiba University Graduate School of MedicineWe investigated age-related change in the contribution of stroke volume (SV) to central PP (cPP). Eighty seven adult subjects who were free of vasoactive agents were included. Subjects were divided into three age groups: young (20–39 years, n = 26), middle (40–49 years, n = 29), and old (≥50 years, n = 32). SV was calculated by Doppler echocardiography. Hemodynamic indices were measured using a brachial cuff-based oscillometric method. The brachial and cPP showed a small decline from the young group to the middle group and a greater rise after 50 years old. SV significantly and positively correlated with brachial (r = 0.53, p < 0.01) and cPP (r = 0.57, p < 0.01) in the young group. In the middle group, the association of SV with brachial pulse pressure was significant (r = 0.38, p = 0.04) and that with cPP was bordering significant (r = 0.34, p = 0.07). No significant association was found between SV and PP in the old group. In conclusion, the contribution of SV to cPP decreases with age. Age-related changes in the determinants of cPP should be considered when investigating the clinical value of cPP.http://dx.doi.org/10.1080/10641963.2016.1259331agingcentral blood pressurepulse pressurestroke volume
spellingShingle Atsushi Nakagomi
Sho Okada
Nobusada Funabashi
Yoshio Kobayashi
Age-related change in contribution of stroke volume to central pulse pressure
Clinical and Experimental Hypertension
aging
central blood pressure
pulse pressure
stroke volume
title Age-related change in contribution of stroke volume to central pulse pressure
title_full Age-related change in contribution of stroke volume to central pulse pressure
title_fullStr Age-related change in contribution of stroke volume to central pulse pressure
title_full_unstemmed Age-related change in contribution of stroke volume to central pulse pressure
title_short Age-related change in contribution of stroke volume to central pulse pressure
title_sort age related change in contribution of stroke volume to central pulse pressure
topic aging
central blood pressure
pulse pressure
stroke volume
url http://dx.doi.org/10.1080/10641963.2016.1259331
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AT nobusadafunabashi agerelatedchangeincontributionofstrokevolumetocentralpulsepressure
AT yoshiokobayashi agerelatedchangeincontributionofstrokevolumetocentralpulsepressure