First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?

Severe sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the first choice of vasoactive agent in adult septic shock flowed by adrenalin...

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Main Authors: Mehak Bansal, Praveen Khilnani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Pediatric Critical Care
Subjects:
Online Access:http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2019;volume=6;issue=2;spage=22;epage=28;aulast=Bansal
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author Mehak Bansal
Praveen Khilnani
author_facet Mehak Bansal
Praveen Khilnani
author_sort Mehak Bansal
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description Severe sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the first choice of vasoactive agent in adult septic shock flowed by adrenaline or vasopressin in cases who do not respond to norepinephrine. In this article we have reviewed the literature and compared noradrenaline and adrenaline as first line vasoactive drug in children with fluid refractory septic shock. We have also discussed the change in the paradigm -use of dopamine as alternative instead of first line vasoactive agent
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spelling doaj.art-e79ed7f9b0394334a67707e69f8ff6b62022-12-21T17:25:24ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992019-01-0162222810.21304/2019.0602.00485First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?Mehak BansalPraveen KhilnaniSevere sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the first choice of vasoactive agent in adult septic shock flowed by adrenaline or vasopressin in cases who do not respond to norepinephrine. In this article we have reviewed the literature and compared noradrenaline and adrenaline as first line vasoactive drug in children with fluid refractory septic shock. We have also discussed the change in the paradigm -use of dopamine as alternative instead of first line vasoactive agenthttp://www.jpcc.org.in/article.asp?issn=2349-6592;year=2019;volume=6;issue=2;spage=22;epage=28;aulast=Bansalpediatric sepsisdopamineadrenalinenoradrenalineseptic shock
spellingShingle Mehak Bansal
Praveen Khilnani
First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
Journal of Pediatric Critical Care
pediatric sepsis
dopamine
adrenaline
noradrenaline
septic shock
title First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
title_full First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
title_fullStr First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
title_full_unstemmed First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
title_short First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
title_sort first line vasoactive therapy after fluid resuscitation in pediatric septic shock dopamine adrenaline or noradrenaline
topic pediatric sepsis
dopamine
adrenaline
noradrenaline
septic shock
url http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2019;volume=6;issue=2;spage=22;epage=28;aulast=Bansal
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AT praveenkhilnani firstlinevasoactivetherapyafterfluidresuscitationinpediatricsepticshockdopamineadrenalineornoradrenaline