First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?
Severe sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the first choice of vasoactive agent in adult septic shock flowed by adrenalin...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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Series: | Journal of Pediatric Critical Care |
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Online Access: | http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2019;volume=6;issue=2;spage=22;epage=28;aulast=Bansal |
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author | Mehak Bansal Praveen Khilnani |
author_facet | Mehak Bansal Praveen Khilnani |
author_sort | Mehak Bansal |
collection | DOAJ |
description | Severe sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the first choice of vasoactive agent in adult septic shock flowed by adrenaline or vasopressin in cases who do not respond to norepinephrine. In this article we have reviewed the literature and compared noradrenaline and adrenaline as first line vasoactive drug in children with fluid refractory septic shock. We have also discussed the change in the paradigm -use of dopamine as alternative instead of first line vasoactive agent |
first_indexed | 2024-12-23T23:51:02Z |
format | Article |
id | doaj.art-e79ed7f9b0394334a67707e69f8ff6b6 |
institution | Directory Open Access Journal |
issn | 2349-6592 2455-7099 |
language | English |
last_indexed | 2024-12-23T23:51:02Z |
publishDate | 2019-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Pediatric Critical Care |
spelling | doaj.art-e79ed7f9b0394334a67707e69f8ff6b62022-12-21T17:25:24ZengWolters Kluwer Medknow PublicationsJournal of Pediatric Critical Care2349-65922455-70992019-01-0162222810.21304/2019.0602.00485First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline?Mehak BansalPraveen KhilnaniSevere sepsis and septic shock are the leading cause of morbidity and mortality in children all over the world, in both developed and developing nations. Surviving Sepsis Guidelines 2016 have recommended norepinephrine as the first choice of vasoactive agent in adult septic shock flowed by adrenaline or vasopressin in cases who do not respond to norepinephrine. In this article we have reviewed the literature and compared noradrenaline and adrenaline as first line vasoactive drug in children with fluid refractory septic shock. We have also discussed the change in the paradigm -use of dopamine as alternative instead of first line vasoactive agenthttp://www.jpcc.org.in/article.asp?issn=2349-6592;year=2019;volume=6;issue=2;spage=22;epage=28;aulast=Bansalpediatric sepsisdopamineadrenalinenoradrenalineseptic shock |
spellingShingle | Mehak Bansal Praveen Khilnani First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline? Journal of Pediatric Critical Care pediatric sepsis dopamine adrenaline noradrenaline septic shock |
title | First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline? |
title_full | First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline? |
title_fullStr | First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline? |
title_full_unstemmed | First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline? |
title_short | First line vasoactive therapy after fluid resuscitation in pediatric septic shock – Dopamine, Adrenaline or Noradrenaline? |
title_sort | first line vasoactive therapy after fluid resuscitation in pediatric septic shock dopamine adrenaline or noradrenaline |
topic | pediatric sepsis dopamine adrenaline noradrenaline septic shock |
url | http://www.jpcc.org.in/article.asp?issn=2349-6592;year=2019;volume=6;issue=2;spage=22;epage=28;aulast=Bansal |
work_keys_str_mv | AT mehakbansal firstlinevasoactivetherapyafterfluidresuscitationinpediatricsepticshockdopamineadrenalineornoradrenaline AT praveenkhilnani firstlinevasoactivetherapyafterfluidresuscitationinpediatricsepticshockdopamineadrenalineornoradrenaline |