Improving Treatment of Giardiasis
Giardiasis is one of the most common parasitic diseases in both children and adults, and is revealed in all countries of the world. Despite the wide range of etiotropic drugs, there remains a need to improve the treatment. The objective of therapy is not only the eradication of the pathogen, but als...
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Format: | Article |
Language: | English |
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Zaslavsky O.Yu.
2015-09-01
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Series: | Aktualʹnaâ Infektologiâ |
Subjects: | |
Online Access: | http://ai.zaslavsky.com.ua/article/view/78705 |
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author | I.B. Yershova H.O. Moсhalova T.F. Osypova O.V. Petrenko |
author_facet | I.B. Yershova H.O. Moсhalova T.F. Osypova O.V. Petrenko |
author_sort | I.B. Yershova |
collection | DOAJ |
description | Giardiasis is one of the most common parasitic diseases in both children and adults, and is revealed in all countries of the world.
Despite the wide range of etiotropic drugs, there remains a need to improve the treatment. The objective of therapy is not only the eradication of the pathogen, but also the elimination of the consequences of its presence in the body. When choosing etiotropic drug for the treatment of giardiasis there has been considered not only the antiparasitic efficacy of Macmiror (nifuratel), but also the safety and good tolerability. The spectrum of antibacterial activity of nifuratel:
— protozoa: Lamblia intestinalis, Trichomonas vaginalis, Entamoeba histolytica;
— pathogenic fungi: Candida albicans, Microsporum spp., Trichophyton spp.;
— bacteria:
– Gram-negative: E.coli, Shigella spp., Salmonella spp., Proteus spp., Klebsiella spp., Vibrio cholerae;
– Gram-positive: Staphylococcus spp., Streptococcus spp., Helicobacter pylori.
The ability of Macmiror to be eliminated by the kidneys almost completely, without involvement of the liver detoxification reserves, is equally important. An examination of the state of eubiosis in children receiving Macmiror has shown a positive effect of the drug on the intestinal microflora. Based on the individual results of the study and review of the literature data, it was found that Macmiror is one of the most effective and safe drug in the treatment of giardiasis. |
first_indexed | 2024-12-24T06:59:15Z |
format | Article |
id | doaj.art-e79f3cbed1444b45a4a55e11cf622056 |
institution | Directory Open Access Journal |
issn | 2312-413X 2312-4148 |
language | English |
last_indexed | 2024-12-24T06:59:15Z |
publishDate | 2015-09-01 |
publisher | Zaslavsky O.Yu. |
record_format | Article |
series | Aktualʹnaâ Infektologiâ |
spelling | doaj.art-e79f3cbed1444b45a4a55e11cf6220562022-12-21T17:09:40ZengZaslavsky O.Yu.Aktualʹnaâ Infektologiâ2312-413X2312-41482015-09-0133.08495410.22141/2312-413x.3.08.2015.7870578705Improving Treatment of GiardiasisI.B. Yershova0H.O. Moсhalova1T.F. Osypova2O.V. Petrenko3Luhansk State Medical University, LuhanskNational Medical University named after O.O. Bohomolets, KyivLuhansk State Medical University, LuhanskLuhansk State Medical University, LuhanskGiardiasis is one of the most common parasitic diseases in both children and adults, and is revealed in all countries of the world. Despite the wide range of etiotropic drugs, there remains a need to improve the treatment. The objective of therapy is not only the eradication of the pathogen, but also the elimination of the consequences of its presence in the body. When choosing etiotropic drug for the treatment of giardiasis there has been considered not only the antiparasitic efficacy of Macmiror (nifuratel), but also the safety and good tolerability. The spectrum of antibacterial activity of nifuratel: — protozoa: Lamblia intestinalis, Trichomonas vaginalis, Entamoeba histolytica; — pathogenic fungi: Candida albicans, Microsporum spp., Trichophyton spp.; — bacteria: – Gram-negative: E.coli, Shigella spp., Salmonella spp., Proteus spp., Klebsiella spp., Vibrio cholerae; – Gram-positive: Staphylococcus spp., Streptococcus spp., Helicobacter pylori. The ability of Macmiror to be eliminated by the kidneys almost completely, without involvement of the liver detoxification reserves, is equally important. An examination of the state of eubiosis in children receiving Macmiror has shown a positive effect of the drug on the intestinal microflora. Based on the individual results of the study and review of the literature data, it was found that Macmiror is one of the most effective and safe drug in the treatment of giardiasis.http://ai.zaslavsky.com.ua/article/view/78705giardiasistreatmentnifuratelMacmiror |
spellingShingle | I.B. Yershova H.O. Moсhalova T.F. Osypova O.V. Petrenko Improving Treatment of Giardiasis Aktualʹnaâ Infektologiâ giardiasis treatment nifuratel Macmiror |
title | Improving Treatment of Giardiasis |
title_full | Improving Treatment of Giardiasis |
title_fullStr | Improving Treatment of Giardiasis |
title_full_unstemmed | Improving Treatment of Giardiasis |
title_short | Improving Treatment of Giardiasis |
title_sort | improving treatment of giardiasis |
topic | giardiasis treatment nifuratel Macmiror |
url | http://ai.zaslavsky.com.ua/article/view/78705 |
work_keys_str_mv | AT ibyershova improvingtreatmentofgiardiasis AT homoshalova improvingtreatmentofgiardiasis AT tfosypova improvingtreatmentofgiardiasis AT ovpetrenko improvingtreatmentofgiardiasis |