Improving Treatment of Giardiasis

Giardiasis is one of the most common parasitic diseases in both children and adults, and is revealed in all countries of the world. Despite the wide range of etiotropic drugs, there remains a need to improve the treatment. The objective of therapy is not only the eradication of the pathogen, but als...

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Main Authors: I.B. Yershova, H.O. Moсhalova, T.F. Osypova, O.V. Petrenko
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2015-09-01
Series:Aktualʹnaâ Infektologiâ
Subjects:
Online Access:http://ai.zaslavsky.com.ua/article/view/78705
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author I.B. Yershova
H.O. Moсhalova
T.F. Osypova
O.V. Petrenko
author_facet I.B. Yershova
H.O. Moсhalova
T.F. Osypova
O.V. Petrenko
author_sort I.B. Yershova
collection DOAJ
description Giardiasis is one of the most common parasitic diseases in both children and adults, and is revealed in all countries of the world. Despite the wide range of etiotropic drugs, there remains a need to improve the treatment. The objective of therapy is not only the eradication of the pathogen, but also the elimination of the consequences of its presence in the body. When choosing etiotropic drug for the treatment of giardiasis there has been considered not only the antiparasitic efficacy of Macmiror (nifuratel), but also the safety and good tolerability. The spectrum of antibacterial activity of nifuratel: — protozoa: Lamblia intestinalis, Trichomonas vaginalis, Entamoeba histolytica; — pathogenic fungi: Candida albicans, Microsporum spp., Trichophyton spp.; — bacteria: – Gram-negative: E.coli, Shigella spp., Salmonella spp., Proteus spp., Klebsiella spp., Vibrio cholerae; – Gram-positive: Staphylococcus spp., Streptococcus spp., Helicobacter pylori. The ability of Macmiror to be eliminated by the kidneys almost completely, without involvement of the liver detoxification reserves, is equally important. An examination of the state of eubiosis in children receiving Macmiror has shown a positive effect of the drug on the intestinal microflora. Based on the individual results of the study and review of the literature data, it was found that Macmiror is one of the most effective and safe drug in the treatment of giardiasis.
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spelling doaj.art-e79f3cbed1444b45a4a55e11cf6220562022-12-21T17:09:40ZengZaslavsky O.Yu.Aktualʹnaâ Infektologiâ2312-413X2312-41482015-09-0133.08495410.22141/2312-413x.3.08.2015.7870578705Improving Treatment of GiardiasisI.B. Yershova0H.O. Moсhalova1T.F. Osypova2O.V. Petrenko3Luhansk State Medical University, LuhanskNational Medical University named after O.O. Bohomolets, KyivLuhansk State Medical University, LuhanskLuhansk State Medical University, LuhanskGiardiasis is one of the most common parasitic diseases in both children and adults, and is revealed in all countries of the world. Despite the wide range of etiotropic drugs, there remains a need to improve the treatment. The objective of therapy is not only the eradication of the pathogen, but also the elimination of the consequences of its presence in the body. When choosing etiotropic drug for the treatment of giardiasis there has been considered not only the antiparasitic efficacy of Macmiror (nifuratel), but also the safety and good tolerability. The spectrum of antibacterial activity of nifuratel: — protozoa: Lamblia intestinalis, Trichomonas vaginalis, Entamoeba histolytica; — pathogenic fungi: Candida albicans, Microsporum spp., Trichophyton spp.; — bacteria: – Gram-negative: E.coli, Shigella spp., Salmonella spp., Proteus spp., Klebsiella spp., Vibrio cholerae; – Gram-positive: Staphylococcus spp., Streptococcus spp., Helicobacter pylori. The ability of Macmiror to be eliminated by the kidneys almost completely, without involvement of the liver detoxification reserves, is equally important. An examination of the state of eubiosis in children receiving Macmiror has shown a positive effect of the drug on the intestinal microflora. Based on the individual results of the study and review of the literature data, it was found that Macmiror is one of the most effective and safe drug in the treatment of giardiasis.http://ai.zaslavsky.com.ua/article/view/78705giardiasistreatmentnifuratelMacmiror
spellingShingle I.B. Yershova
H.O. Moсhalova
T.F. Osypova
O.V. Petrenko
Improving Treatment of Giardiasis
Aktualʹnaâ Infektologiâ
giardiasis
treatment
nifuratel
Macmiror
title Improving Treatment of Giardiasis
title_full Improving Treatment of Giardiasis
title_fullStr Improving Treatment of Giardiasis
title_full_unstemmed Improving Treatment of Giardiasis
title_short Improving Treatment of Giardiasis
title_sort improving treatment of giardiasis
topic giardiasis
treatment
nifuratel
Macmiror
url http://ai.zaslavsky.com.ua/article/view/78705
work_keys_str_mv AT ibyershova improvingtreatmentofgiardiasis
AT homoshalova improvingtreatmentofgiardiasis
AT tfosypova improvingtreatmentofgiardiasis
AT ovpetrenko improvingtreatmentofgiardiasis