Elevated soluble TNFα levels and upregulated TNFα mRNA expression in purified peripheral blood monocyte subsets associated with high-grade hepatocellular carcinoma

Elevated soluble TNFα levels and upregulated TNFα mRNA expression in purified peripheral blood monocyte subsets associated with high-grade hepatocellular carcinoma

Abstract Background Chronic inflammation is involved in the initiation and progression of various cancers, including liver cancer. The current study focuses on the characterization of the peripheral immune response in hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) patients, before and a...

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Bibliographic Details
Main Authors: C. Martín-Sierra, R. Martins, M. Coucelo, A. M. Abrantes, R. C. Oliveira, J. G. Tralhão, M. F. Botelho, E. Furtado, M. R. Domingues, A. Paiva, P. Laranjeira
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Inflammation
Subjects:
Flow cytometry
qRT-PCR
Hepatocellular carcinoma
Cholangiocarcinoma
Circulating monocytes
TNFα
Online Access:http://link.springer.com/article/10.1186/s12950-020-00243-7

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