Hortensins, Type 1 Ribosome-Inactivating Proteins from Seeds of Red Mountain Spinach: Isolation, Characterization, and Their Effect on Glioblastoma Cells

Hortensins, Type 1 Ribosome-Inactivating Proteins from Seeds of Red Mountain Spinach: Isolation, Characterization, and Their Effect on Glioblastoma Cells

Ribosome inactivating proteins (RIPs) are specific N-β-glycosylases that are well-characterized in plants. Their enzymatic action is to damage ribosomes, thereby blocking protein translation. Recently, several research groups have been working on the screening for these toxins in edible plants to fa...

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Bibliographic Details
Main Authors: Sara Ragucci, Veronica Russo, Angela Clemente, Maria Giuseppina Campanile, Maria Antonietta Oliva, Nicola Landi, Paolo Vincenzo Pedone, Antonietta Arcella, Antimo Di Maro
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Toxins
Subjects:
<i>Atriplex hortensis</i> L.
cytotoxicity
edible plants
red orache
rRNA N-glycosylases
U87MG glioblastoma cells
Online Access:https://www.mdpi.com/2072-6651/16/3/135

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