Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes
Abstract The gestational weight gain (GWG) range of Chinese women with gestational diabetes mellitus (GDM) remains unclear. Our objective was to identify the ranges of GWG in Chinese women with GDM and to investigate the associations between prepregnancy body mass index (BMI), GWG and maternal-infan...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-06733-3 |
| _version_ | 1819279494325731328 |
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| author | Qing-Xiang Zheng Hai-Wei Wang Xiu-Min Jiang Yan Lin Gui-Hua Liu Mian Pan Li Ge Xiao-Qian Chen Jing-Ling Wu Xiao-Yun Zhang Yu-Qing Pan Hong-Gu He |
| author_facet | Qing-Xiang Zheng Hai-Wei Wang Xiu-Min Jiang Yan Lin Gui-Hua Liu Mian Pan Li Ge Xiao-Qian Chen Jing-Ling Wu Xiao-Yun Zhang Yu-Qing Pan Hong-Gu He |
| author_sort | Qing-Xiang Zheng |
| collection | DOAJ |
| description | Abstract The gestational weight gain (GWG) range of Chinese women with gestational diabetes mellitus (GDM) remains unclear. Our objective was to identify the ranges of GWG in Chinese women with GDM and to investigate the associations between prepregnancy body mass index (BMI), GWG and maternal-infant adverse outcomes. Cases of GDM women who delivered singletons from 2013 to 2018 in a public hospital were collected. Logistic regression analysis was used to assess the joint effects of prepregnancy BMI and GWG on maternal-infant adverse outcomes. Ultimately, 14,578 women were collected. The ranges of GWG in Chinese women with GDM were different from the National Academy of Medicine’s (NAM) recommendation. The ranges of GWG of Chinese women with GDM in the underweight, normal weight, overweight and obese groups were 5.95–21.95 kg, 4.23–21.83 kg, 0.88–21.12 kg and − 1.76 to 19.95 kg, respectively. The risks of large for gestational age (LGA), macrosomia and caesarean delivery were significantly increased with the increasing prepregnancy BMI. Furthermore, the risks of LGA, macrosomia and caesarean delivery were significantly higher in the normal weight group with a GWG higher than the NAM recommendation. Similarly, in the overweight group with a GWG higher than the NAM recommendation, the risks of LGA were significantly higher, while the risks of macrosomia were significantly lower. Overall, we determined the range of GWG in different prepregnancy BMI groups. And GDM women with high prepregnancy BMI and excessive GWG were associated with the higher risks of maternal-infants adverse outcomes in China. |
| first_indexed | 2024-12-24T00:28:48Z |
| format | Article |
| id | doaj.art-e7a47512ae884b00bc176d18e4d1087f |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-24T00:28:48Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-e7a47512ae884b00bc176d18e4d1087f2022-12-21T17:24:20ZengNature PortfolioScientific Reports2045-23222022-02-0112111010.1038/s41598-022-06733-3Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetesQing-Xiang Zheng0Hai-Wei Wang1Xiu-Min Jiang2Yan Lin3Gui-Hua Liu4Mian Pan5Li Ge6Xiao-Qian Chen7Jing-Ling Wu8Xiao-Yun Zhang9Yu-Qing Pan10Hong-Gu He11Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversitySchool of Nursing, Fujian University of Traditional Chinese MedicineFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical UniversityAlice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of SingaporeAbstract The gestational weight gain (GWG) range of Chinese women with gestational diabetes mellitus (GDM) remains unclear. Our objective was to identify the ranges of GWG in Chinese women with GDM and to investigate the associations between prepregnancy body mass index (BMI), GWG and maternal-infant adverse outcomes. Cases of GDM women who delivered singletons from 2013 to 2018 in a public hospital were collected. Logistic regression analysis was used to assess the joint effects of prepregnancy BMI and GWG on maternal-infant adverse outcomes. Ultimately, 14,578 women were collected. The ranges of GWG in Chinese women with GDM were different from the National Academy of Medicine’s (NAM) recommendation. The ranges of GWG of Chinese women with GDM in the underweight, normal weight, overweight and obese groups were 5.95–21.95 kg, 4.23–21.83 kg, 0.88–21.12 kg and − 1.76 to 19.95 kg, respectively. The risks of large for gestational age (LGA), macrosomia and caesarean delivery were significantly increased with the increasing prepregnancy BMI. Furthermore, the risks of LGA, macrosomia and caesarean delivery were significantly higher in the normal weight group with a GWG higher than the NAM recommendation. Similarly, in the overweight group with a GWG higher than the NAM recommendation, the risks of LGA were significantly higher, while the risks of macrosomia were significantly lower. Overall, we determined the range of GWG in different prepregnancy BMI groups. And GDM women with high prepregnancy BMI and excessive GWG were associated with the higher risks of maternal-infants adverse outcomes in China.https://doi.org/10.1038/s41598-022-06733-3 |
| spellingShingle | Qing-Xiang Zheng Hai-Wei Wang Xiu-Min Jiang Yan Lin Gui-Hua Liu Mian Pan Li Ge Xiao-Qian Chen Jing-Ling Wu Xiao-Yun Zhang Yu-Qing Pan Hong-Gu He Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes Scientific Reports |
| title | Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes |
| title_full | Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes |
| title_fullStr | Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes |
| title_full_unstemmed | Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes |
| title_short | Prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in Chinese women with gestational diabetes |
| title_sort | prepregnancy body mass index and gestational weight gain are associated with maternal and infant adverse outcomes in chinese women with gestational diabetes |
| url | https://doi.org/10.1038/s41598-022-06733-3 |
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