Scar sarcoidosis on 18F-FDG PET/CT
18F-labeled fluoro-2-deoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) is an important imaging modality in the clinical workup of patients with chronic inflammatory disorders which present quite often with a fever of unknown origin. Sarcoidosis is a multisystem chronic...
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| Format: | Article |
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Mashhad University of Medical Sciences
2019-06-01
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| Series: | Asia Oceania Journal of Nuclear Medicine and Biology |
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| Online Access: | http://aojnmb.mums.ac.ir/article_13357_48c47519112c2e2bccf099a4a3a7fefc.pdf |
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| author | Saurabh Arora Nishikant Avinash Damle Averilicia Passah Animesh Ray Manish Soneja Sayantan Banerjee Seema Kaushal Manisha Jana Madhavi Tripathi Chandrasekhar Bal |
| author_facet | Saurabh Arora Nishikant Avinash Damle Averilicia Passah Animesh Ray Manish Soneja Sayantan Banerjee Seema Kaushal Manisha Jana Madhavi Tripathi Chandrasekhar Bal |
| author_sort | Saurabh Arora |
| collection | DOAJ |
| description | 18F-labeled fluoro-2-deoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) is an important imaging modality in the clinical workup of patients with chronic inflammatory disorders which present quite often with a fever of unknown origin. Sarcoidosis is a multisystem chronic inflammatory disorder with a wide clinical spectrum that can involve different organs. The diagnosis of sarcoidosis is usually based on the observation of noncaseating granulomas in biopsy specimens and exclusion of other granulomatous diseases. Skin involvement can occur in 20-25% of sarcoidosis cases. However, scar involvement in sarcoidosis is a rare condition. Herein, we present a case of multisystem sarcoidosis in a 45-year-old woman, who was previously treated with steroids and was in remission for 8 months. The patient presented with multiple skin nodules on the chest and back, a history of intermittent fever, headache, and mild itching at the abdominal scar site for 3 months. Blood investigations revealed elevated serum angiotensin-converting enzyme levels. The 18F-FDG PET/CT revealed a metabolically active involvement of the cutaneous tissue (posthysterectomy scar), apart from other sites of involvement. Biopsy of the scar site revealed multiple epithelioid cell granulomas with giant cells surrounding the collagenous fibers of the scar tissue |
| first_indexed | 2024-12-13T02:31:57Z |
| format | Article |
| id | doaj.art-e7a9e5516e324e74b364b5cabd0c0aa5 |
| institution | Directory Open Access Journal |
| issn | 2322-5718 2322-5726 |
| language | English |
| last_indexed | 2024-12-13T02:31:57Z |
| publishDate | 2019-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Asia Oceania Journal of Nuclear Medicine and Biology |
| spelling | doaj.art-e7a9e5516e324e74b364b5cabd0c0aa52022-12-22T00:02:30ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262019-06-017218518710.22038/aojnmb.2019.37888.125313357Scar sarcoidosis on 18F-FDG PET/CTSaurabh Arora0Nishikant Avinash Damle1Averilicia Passah2Animesh Ray3Manish Soneja4Sayantan Banerjee5Seema Kaushal6Manisha Jana7Madhavi Tripathi8Chandrasekhar Bal9Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India18F-labeled fluoro-2-deoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) is an important imaging modality in the clinical workup of patients with chronic inflammatory disorders which present quite often with a fever of unknown origin. Sarcoidosis is a multisystem chronic inflammatory disorder with a wide clinical spectrum that can involve different organs. The diagnosis of sarcoidosis is usually based on the observation of noncaseating granulomas in biopsy specimens and exclusion of other granulomatous diseases. Skin involvement can occur in 20-25% of sarcoidosis cases. However, scar involvement in sarcoidosis is a rare condition. Herein, we present a case of multisystem sarcoidosis in a 45-year-old woman, who was previously treated with steroids and was in remission for 8 months. The patient presented with multiple skin nodules on the chest and back, a history of intermittent fever, headache, and mild itching at the abdominal scar site for 3 months. Blood investigations revealed elevated serum angiotensin-converting enzyme levels. The 18F-FDG PET/CT revealed a metabolically active involvement of the cutaneous tissue (posthysterectomy scar), apart from other sites of involvement. Biopsy of the scar site revealed multiple epithelioid cell granulomas with giant cells surrounding the collagenous fibers of the scar tissuehttp://aojnmb.mums.ac.ir/article_13357_48c47519112c2e2bccf099a4a3a7fefc.pdfScar sarcoidosis18F-FDG PET/CTcutaneous sarcoidosis |
| spellingShingle | Saurabh Arora Nishikant Avinash Damle Averilicia Passah Animesh Ray Manish Soneja Sayantan Banerjee Seema Kaushal Manisha Jana Madhavi Tripathi Chandrasekhar Bal Scar sarcoidosis on 18F-FDG PET/CT Asia Oceania Journal of Nuclear Medicine and Biology Scar sarcoidosis 18F-FDG PET/CT cutaneous sarcoidosis |
| title | Scar sarcoidosis on 18F-FDG PET/CT |
| title_full | Scar sarcoidosis on 18F-FDG PET/CT |
| title_fullStr | Scar sarcoidosis on 18F-FDG PET/CT |
| title_full_unstemmed | Scar sarcoidosis on 18F-FDG PET/CT |
| title_short | Scar sarcoidosis on 18F-FDG PET/CT |
| title_sort | scar sarcoidosis on 18f fdg pet ct |
| topic | Scar sarcoidosis 18F-FDG PET/CT cutaneous sarcoidosis |
| url | http://aojnmb.mums.ac.ir/article_13357_48c47519112c2e2bccf099a4a3a7fefc.pdf |
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