Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol
Beta-adrenoblockers, included in any cardiovascular disease treatment standard, became a key part of clinical practice only in late XX century. Nebivolol is a highly selective beta-1 -adrenoiblocker, modulating endothelial NO release and subsequent physiological vasodilatation. Nebivolol has multipl...
Main Authors: | , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
«SILICEA-POLIGRAF» LLC
1970-01-01
|
Series: | Кардиоваскулярная терапия и профилактика |
Subjects: | |
Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1799 |
_version_ | 1797882845392273408 |
---|---|
author | V. I. Makolkin D. A. Napalkov |
author_facet | V. I. Makolkin D. A. Napalkov |
author_sort | V. I. Makolkin |
collection | DOAJ |
description | Beta-adrenoblockers, included in any cardiovascular disease treatment standard, became a key part of clinical practice only in late XX century. Nebivolol is a highly selective beta-1 -adrenoiblocker, modulating endothelial NO release and subsequent physiological vasodilatation. Nebivolol has multiple clinical indications, including coronary heart disease, arterial hypertension, and chronic heart failure. Due to its super-selectivity it can also be beneficial in patients with diabetes mellitus, chronic obstructive pulmonary disease, and erectile dysfunction. |
first_indexed | 2024-04-10T03:42:10Z |
format | Article |
id | doaj.art-e7a9f5ec70b549fcbc0e8ef4bb3f233c |
institution | Directory Open Access Journal |
issn | 1728-8800 2619-0125 |
language | Russian |
last_indexed | 2024-04-10T03:42:10Z |
publishDate | 1970-01-01 |
publisher | «SILICEA-POLIGRAF» LLC |
record_format | Article |
series | Кардиоваскулярная терапия и профилактика |
spelling | doaj.art-e7a9f5ec70b549fcbc0e8ef4bb3f233c2023-03-13T07:23:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-01581091161514Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivololV. I. Makolkin0D. A. Napalkov1Московская медицинская академия им. И.М.Сеченова. МоскваМосковская медицинская академия им. И.М.Сеченова. МоскваBeta-adrenoblockers, included in any cardiovascular disease treatment standard, became a key part of clinical practice only in late XX century. Nebivolol is a highly selective beta-1 -adrenoiblocker, modulating endothelial NO release and subsequent physiological vasodilatation. Nebivolol has multiple clinical indications, including coronary heart disease, arterial hypertension, and chronic heart failure. Due to its super-selectivity it can also be beneficial in patients with diabetes mellitus, chronic obstructive pulmonary disease, and erectile dysfunction.https://cardiovascular.elpub.ru/jour/article/view/1799β-адреноблокаторынебивололишемическая болезнь сердцаартериальная гипертензиясердечная недостаточность |
spellingShingle | V. I. Makolkin D. A. Napalkov Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol Кардиоваскулярная терапия и профилактика β-адреноблокаторы небиволол ишемическая болезнь сердца артериальная гипертензия сердечная недостаточность |
title | Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol |
title_full | Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol |
title_fullStr | Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol |
title_full_unstemmed | Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol |
title_short | Modern therapeutic potential of super-selective β<sup>1</sup>-adrenoblocker nebivolol |
title_sort | modern therapeutic potential of super selective β sup 1 sup adrenoblocker nebivolol |
topic | β-адреноблокаторы небиволол ишемическая болезнь сердца артериальная гипертензия сердечная недостаточность |
url | https://cardiovascular.elpub.ru/jour/article/view/1799 |
work_keys_str_mv | AT vimakolkin moderntherapeuticpotentialofsuperselectivebsup1supadrenoblockernebivolol AT danapalkov moderntherapeuticpotentialofsuperselectivebsup1supadrenoblockernebivolol |