Protocol for Sonogashira coupling of alkynes and aryl halides via nickel catalysis
Summary: Alkynes are widely present in natural products and pharmaceutical compounds. Here, we present a protocol for nickel-catalyzed cross-coupling of terminal alkynes with aryl iodides or bromides for constructing a C(sp2)-C(sp) bond. We describe steps for reagent preparation, reaction setup, pur...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Elsevier
2024-03-01
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| Colección: | STAR Protocols |
| Materias: | |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S2666166724000650 |