Potential Protective Effect of Dengue NS1 Human Monoclonal Antibodies against Dengue and Zika Virus Infections

Potential Protective Effect of Dengue NS1 Human Monoclonal Antibodies against Dengue and Zika Virus Infections

Due to the lack of an effective therapeutic treatment to flavivirus, dengue virus (DENV) nonstructural protein 1 (NS1) has been considered to develop a vaccine owing to its lack of a role in antibody-dependent enhancement (ADE). However, both NS1 and its antibody have shown cross-reactivity to host...

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Bibliographic Details
Main Authors: Rochanawan Sootichote, Wilarat Puangmanee, Surachet Benjathummarak, Siriporn Kowaboot, Atsushi Yamanaka, Korbporn Boonnak, Sumate Ampawong, Supawat Chatchen, Pongrama Ramasoota, Pannamthip Pitaksajjakul
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomedicines
Subjects:
dengue virus
Zika virus
dengue non-structural protein 1
human monoclonal antibody
neutralization
vascular leakage
Online Access:https://www.mdpi.com/2227-9059/11/1/227

Internet

https://www.mdpi.com/2227-9059/11/1/227

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