Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials
Jianrong Wang,* Danni Dai,* Hanshu Xie, Dan Li, Gege Xiong, Chao Zhang Stomatological Hospital, Southern Medical University, Guangzhou, 510280, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Zhang, Email 2645491781@qq.comAbstract...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-12-01
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| Series: | International Journal of Nanomedicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/biological-effects-applications-and-design-strategies-of-medical-polyu-peer-reviewed-fulltext-article-IJN |
| _version_ | 1797974870971121664 |
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| author | Wang J Dai D Xie H Li D Xiong G Zhang C |
| author_facet | Wang J Dai D Xie H Li D Xiong G Zhang C |
| author_sort | Wang J |
| collection | DOAJ |
| description | Jianrong Wang,* Danni Dai,* Hanshu Xie, Dan Li, Gege Xiong, Chao Zhang Stomatological Hospital, Southern Medical University, Guangzhou, 510280, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Zhang, Email 2645491781@qq.comAbstract: Polyurethane (PU) has wide application and popularity as medical apparatus due to its unique structural properties relationship. However, there are still some problems with medical PUs, such as a lack of functionality, insufficient long-term implantation safety, undesired stability, etc. With the rapid development of nanotechnology, the nanomodification of medical PU provides new solutions to these clinical problems. The introduction of nanomaterials could optimize the biocompatibility, antibacterial effect, mechanical strength, and degradation of PUs via blending or surface modification, therefore expanding the application range of medical PUs. This review summarizes the current applications of nano-modified medical PUs in diverse fields. Furthermore, the underlying mechanisms in efficiency optimization are analyzed in terms of the enhanced biological and mechanical properties critical for medical use. We also conclude the preparation schemes and related parameters of nano-modified medical PUs, with discussions about the limitations and prospects. This review indicates the current status of nano-modified medical PUs and contributes to inspiring novel and appropriate designing of PUs for desired clinical requirements.Graphical Abstarct: Keywords: polyurethane, nanomaterial, modification, medical application |
| first_indexed | 2024-04-11T04:26:34Z |
| format | Article |
| id | doaj.art-e7b1df99b36d4feabb025c1df827fa90 |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-04-11T04:26:34Z |
| publishDate | 2022-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-e7b1df99b36d4feabb025c1df827fa902022-12-29T17:48:02ZengDove Medical PressInternational Journal of Nanomedicine1178-20132022-12-01Volume 176791681980690Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by NanomaterialsWang JDai DXie HLi DXiong GZhang CJianrong Wang,* Danni Dai,* Hanshu Xie, Dan Li, Gege Xiong, Chao Zhang Stomatological Hospital, Southern Medical University, Guangzhou, 510280, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Zhang, Email 2645491781@qq.comAbstract: Polyurethane (PU) has wide application and popularity as medical apparatus due to its unique structural properties relationship. However, there are still some problems with medical PUs, such as a lack of functionality, insufficient long-term implantation safety, undesired stability, etc. With the rapid development of nanotechnology, the nanomodification of medical PU provides new solutions to these clinical problems. The introduction of nanomaterials could optimize the biocompatibility, antibacterial effect, mechanical strength, and degradation of PUs via blending or surface modification, therefore expanding the application range of medical PUs. This review summarizes the current applications of nano-modified medical PUs in diverse fields. Furthermore, the underlying mechanisms in efficiency optimization are analyzed in terms of the enhanced biological and mechanical properties critical for medical use. We also conclude the preparation schemes and related parameters of nano-modified medical PUs, with discussions about the limitations and prospects. This review indicates the current status of nano-modified medical PUs and contributes to inspiring novel and appropriate designing of PUs for desired clinical requirements.Graphical Abstarct: Keywords: polyurethane, nanomaterial, modification, medical applicationhttps://www.dovepress.com/biological-effects-applications-and-design-strategies-of-medical-polyu-peer-reviewed-fulltext-article-IJNpolyurethanenanomaterialmodificationmedical application. |
| spellingShingle | Wang J Dai D Xie H Li D Xiong G Zhang C Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials International Journal of Nanomedicine polyurethane nanomaterial modification medical application. |
| title | Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials |
| title_full | Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials |
| title_fullStr | Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials |
| title_full_unstemmed | Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials |
| title_short | Biological Effects, Applications and Design Strategies of Medical Polyurethanes Modified by Nanomaterials |
| title_sort | biological effects applications and design strategies of medical polyurethanes modified by nanomaterials |
| topic | polyurethane nanomaterial modification medical application. |
| url | https://www.dovepress.com/biological-effects-applications-and-design-strategies-of-medical-polyu-peer-reviewed-fulltext-article-IJN |
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