Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from <i>Rosmarinus officinalis</i> against Alzheimer’s Disease

Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from <i>Rosmarinus officinalis</i> against Alzheimer’s Disease

Alzheimer’s disease (AD) has been associated with the hallmark features of cholinergic dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic transmission, which makes the associated proteins, such as β-site amyloid precursor protein cleaving enzyme 1 (BACE I), acetylcholine esterase (AChE...

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Bibliographic Details
Main Authors: Fatima Javed Mirza, Saadia Zahid, Sanila Amber, Sumera, Hira Jabeen, Noreen Asim, Syed Adnan Ali Shah
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
Alzheimer’s disease
<i>Rosmarinus officinalis</i>
AChE
BACE I
Synapsin I, II, III
docking
Online Access:https://www.mdpi.com/1420-3049/27/21/7241

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