The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status
Background: H. pylori gastritis can be related to people with obesity and metabolic syndrome. The mechanism underlying the relationship between them is suspected to be caused by adipocytokine called resistin. Objective: to analyze the difference level of resistin between positive and negative H. pyl...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2020-09-01
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| Series: | The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy |
| Subjects: | |
| Online Access: | https://www.ina-jghe.com/index.php/jghe/article/view/739 |
| _version_ | 1797810529753890816 |
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| author | Widya Deli Satuti Gontar Alamsyah Siregar Dharma Lindarto Imelda Rey |
| author_facet | Widya Deli Satuti Gontar Alamsyah Siregar Dharma Lindarto Imelda Rey |
| author_sort | Widya Deli Satuti |
| collection | DOAJ |
| description | Background: H. pylori gastritis can be related to people with obesity and metabolic syndrome. The mechanism underlying the relationship between them is suspected to be caused by adipocytokine called resistin. Objective: to analyze the difference level of resistin between positive and negative H. pylori gastritis patients and their relationship with nutritional status.
Method: This cross sectional study was done in the Gastroenterology department of General Hospital Adam Malik, Medan, from May to October 2019. Patients with gastritis diagnosed by endoscopy underwent rapid urease test (RUT), resistin, albumin, hemoglobin tests, also body mass index (BMI) and waist circumference (WC) were measured.
Results: Sixty gastritis patients found by endoscopic examination, 29 (48.33%) was H. pylori positive and 31 (51.67%) was negative. No significant differences were found between BMI, WC, and albumin against H. pylori gastritis with p values 0.099, 0.055, and 0.528, respectively. Hemoglobin was found significant with a p 0.009. The mean resistin in the positive H. pylori group was 7.62 ng/ml while the negative was 3.23 ng/ml, and statistically significant (p 0.001). There was a strong positive correlation between resistin levels with BMI and WC (BMI p 0.01, r 0.577; WC p 0.001, r 0.592).
Conclusion: Resistin levels in gastritis with H. pylori positive are higher than H. pylori negative, body mass index and waist circumference have a strong relationship with resistin levels in patients with positive H. pylori gastritis, hemoglobin is lower in H. pylori positive than negative gastritis. |
| first_indexed | 2024-03-13T07:10:16Z |
| format | Article |
| id | doaj.art-e7b78d3a8ba34ebdb11453ed1c452760 |
| institution | Directory Open Access Journal |
| issn | 1411-4801 2302-8181 |
| language | English |
| last_indexed | 2024-03-13T07:10:16Z |
| publishDate | 2020-09-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy |
| spelling | doaj.art-e7b78d3a8ba34ebdb11453ed1c4527602023-06-06T04:42:02ZengInterna PublishingThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy1411-48012302-81812020-09-0121211411910.24871/2122020114-119705The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional StatusWidya Deli Satuti0Gontar Alamsyah Siregar1Dharma Lindarto2Imelda Rey3Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, MedanDivision of Gastroentero-hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, MedanDivision of Metabolic and Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, MedanDivision of Gastroentero-hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, MedanBackground: H. pylori gastritis can be related to people with obesity and metabolic syndrome. The mechanism underlying the relationship between them is suspected to be caused by adipocytokine called resistin. Objective: to analyze the difference level of resistin between positive and negative H. pylori gastritis patients and their relationship with nutritional status. Method: This cross sectional study was done in the Gastroenterology department of General Hospital Adam Malik, Medan, from May to October 2019. Patients with gastritis diagnosed by endoscopy underwent rapid urease test (RUT), resistin, albumin, hemoglobin tests, also body mass index (BMI) and waist circumference (WC) were measured. Results: Sixty gastritis patients found by endoscopic examination, 29 (48.33%) was H. pylori positive and 31 (51.67%) was negative. No significant differences were found between BMI, WC, and albumin against H. pylori gastritis with p values 0.099, 0.055, and 0.528, respectively. Hemoglobin was found significant with a p 0.009. The mean resistin in the positive H. pylori group was 7.62 ng/ml while the negative was 3.23 ng/ml, and statistically significant (p 0.001). There was a strong positive correlation between resistin levels with BMI and WC (BMI p 0.01, r 0.577; WC p 0.001, r 0.592). Conclusion: Resistin levels in gastritis with H. pylori positive are higher than H. pylori negative, body mass index and waist circumference have a strong relationship with resistin levels in patients with positive H. pylori gastritis, hemoglobin is lower in H. pylori positive than negative gastritis.https://www.ina-jghe.com/index.php/jghe/article/view/739resistin, gastritishelicobacter pyloribody mass indexobesity |
| spellingShingle | Widya Deli Satuti Gontar Alamsyah Siregar Dharma Lindarto Imelda Rey The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy resistin, gastritis helicobacter pylori body mass index obesity |
| title | The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status |
| title_full | The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status |
| title_fullStr | The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status |
| title_full_unstemmed | The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status |
| title_short | The Differences Level of Resistin between Positive and Negative Helicobacter pylori Gastritis and its Correlation with Nutritional Status |
| title_sort | differences level of resistin between positive and negative helicobacter pylori gastritis and its correlation with nutritional status |
| topic | resistin, gastritis helicobacter pylori body mass index obesity |
| url | https://www.ina-jghe.com/index.php/jghe/article/view/739 |
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