Prolonged ventricular pause associated with ticagrelor use: A case report

Abstract Case We report a case of a 76‐year‐old female who presented with non‐ST elevation myocardial infarction and developed a 22‐second ventricular pause with ticagrelor that did not recur after shifting to clopidogrel. Based on the Naranjo algorithm, the likelihood that our patient's prolon...

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Main Authors: Alaa Rahhal, Amer Aljundi, Sara Saeed Ibrahim Mohamed, Muhammad Awais Arif, Abdul Rahman Arabi
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.5017
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author Alaa Rahhal
Amer Aljundi
Sara Saeed Ibrahim Mohamed
Muhammad Awais Arif
Abdul Rahman Arabi
author_facet Alaa Rahhal
Amer Aljundi
Sara Saeed Ibrahim Mohamed
Muhammad Awais Arif
Abdul Rahman Arabi
author_sort Alaa Rahhal
collection DOAJ
description Abstract Case We report a case of a 76‐year‐old female who presented with non‐ST elevation myocardial infarction and developed a 22‐second ventricular pause with ticagrelor that did not recur after shifting to clopidogrel. Based on the Naranjo algorithm, the likelihood that our patient's prolonged ventricular pause was due to ticagrelor exposure was probable. Conclusion Ticagrelor use is associated with prolonged ventricular pauses, warranting close monitoring, particularly during the first week of therapy.
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spelling doaj.art-e7c15071a8fc4c43a6bcbdeb5575a4aa2022-12-21T19:19:41ZengWileyClinical Case Reports2050-09042021-10-01910n/an/a10.1002/ccr3.5017Prolonged ventricular pause associated with ticagrelor use: A case reportAlaa Rahhal0Amer Aljundi1Sara Saeed Ibrahim Mohamed2Muhammad Awais Arif3Abdul Rahman Arabi4Pharmacy Department Heart Hospital Hamad Medical Corporation Doha QatarPharmacy Department Heart Hospital Hamad Medical Corporation Doha QatarInternal Medicine Department, Hamad General Hospital Hamad Medical Corporation Doha QatarCardiology Department, Heart Hospital Hamad Medical Corporation Doha QatarCardiology Department, Heart Hospital Hamad Medical Corporation Doha QatarAbstract Case We report a case of a 76‐year‐old female who presented with non‐ST elevation myocardial infarction and developed a 22‐second ventricular pause with ticagrelor that did not recur after shifting to clopidogrel. Based on the Naranjo algorithm, the likelihood that our patient's prolonged ventricular pause was due to ticagrelor exposure was probable. Conclusion Ticagrelor use is associated with prolonged ventricular pauses, warranting close monitoring, particularly during the first week of therapy.https://doi.org/10.1002/ccr3.5017adverse drug reactionticagrelorventricular pause
spellingShingle Alaa Rahhal
Amer Aljundi
Sara Saeed Ibrahim Mohamed
Muhammad Awais Arif
Abdul Rahman Arabi
Prolonged ventricular pause associated with ticagrelor use: A case report
Clinical Case Reports
adverse drug reaction
ticagrelor
ventricular pause
title Prolonged ventricular pause associated with ticagrelor use: A case report
title_full Prolonged ventricular pause associated with ticagrelor use: A case report
title_fullStr Prolonged ventricular pause associated with ticagrelor use: A case report
title_full_unstemmed Prolonged ventricular pause associated with ticagrelor use: A case report
title_short Prolonged ventricular pause associated with ticagrelor use: A case report
title_sort prolonged ventricular pause associated with ticagrelor use a case report
topic adverse drug reaction
ticagrelor
ventricular pause
url https://doi.org/10.1002/ccr3.5017
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AT ameraljundi prolongedventricularpauseassociatedwithticagreloruseacasereport
AT sarasaeedibrahimmohamed prolongedventricularpauseassociatedwithticagreloruseacasereport
AT muhammadawaisarif prolongedventricularpauseassociatedwithticagreloruseacasereport
AT abdulrahmanarabi prolongedventricularpauseassociatedwithticagreloruseacasereport