Synthesis and Biological Activity Evaluation of 2-Cyanopyrrole Derivatives as Potential Tyrosinase Inhibitors
In order to find potential inhibitors of tyrosinase, two series of pyrrole derivatives A (1–17) and B (1–8) were synthesized and screened for their inhibitory activities on tyrosinase. Most of the 2-cyanopyrrole derivatives exhibited effective inhibitory activities. In particular, A12 exhibited the...
Main Authors: | Ya-Guang Hu, Zhu-Peng Gao, Ying-Ying Zheng, Chun-Mei Hu, Jing Lin, Xiao-Zheng Wu, Xin Zhang, Yong-Sheng Zhou, Zhuang Xiong, Dao-Yong Zhu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-06-01
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Series: | Frontiers in Chemistry |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.914944/full |
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