Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance

Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance

Objective: The peptide hormone adropin regulates fuel selection preferences in skeletal muscle under fed and fasted conditions. Here, we investigated whether adropin treatment can ameliorate the dysregulation of fuel substrate metabolism, and improve aspects of glucose homeostasis in diet-induced ob...

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Bibliographic Details
Main Authors: Su Gao, Ryan P. McMillan, Qingzhang Zhu, Gary D. Lopaschuk, Matthew W. Hulver, Andrew A. Butler
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Molecular Metabolism
Subjects:
Adropin
Glucose metabolism
Fatty acid metabolism
Insulin action
Metabolic flexibility
Mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781500006X

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