Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review
Aim:To evaluate subclinical inflammatory markers in hyperemesis gravidarum (HEG) cases and to determine the relationship of these markers with the gestational age at delivery and birth weight in pregnant women with HEG.Methods:Fifty-two patients who presented to our hospital between 1 May 2017 and 1...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2021-03-01
|
| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/can-subclinical-nflammatory-markers-predict-birth-/46905
|
| _version_ | 1797909795300179968 |
|---|---|
| author | Melike Demir Caltekin Ibrahim Caltekin Taylan Onat Demet Aydogan Kirmizi Emre Baser Serenat Eris Yalcin Mustafa Kara Ethem Serdar Yalvac |
| author_facet | Melike Demir Caltekin Ibrahim Caltekin Taylan Onat Demet Aydogan Kirmizi Emre Baser Serenat Eris Yalcin Mustafa Kara Ethem Serdar Yalvac |
| author_sort | Melike Demir Caltekin |
| collection | DOAJ |
| description | Aim:To evaluate subclinical inflammatory markers in hyperemesis gravidarum (HEG) cases and to determine the relationship of these markers with the gestational age at delivery and birth weight in pregnant women with HEG.Methods:Fifty-two patients who presented to our hospital between 1 May 2017 and 1 September 2019 with HEG and 60 pregnant women as the control group were included in this retrospectively designed study. The relationship of subclinical inflammatory markers such as the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the lymphocyte-to-monocyte ratio (LMR) with HEG, and their relationship with birth week and birth weight in HEG cases were examined.Results:In HEG cases, NLR and PLR values were higher (p=0.006 and p=0.004, respectively), whereas LMR values were lower (p<0.001). In HEG cases, gestational age at delivery had a negative correlation with NLR and PLR and positive correlation with LMR (r=-0.567, p<0.001; r=-0.322, p=0.02, and r=0.279 p=0.045, respectively). In addition, NLR and PLR had negative correlations with birth weight (r=-0.582, p<0.001; r=-0.302, p=0.029, respectively).Conclusion:While NLR and PLR values increase in HEG cases, LMR value decreases. It has been determined that varying rates of subclinical inflammatory markers in HEG are associated with preterm birth week and low birth weight. |
| first_indexed | 2024-04-10T11:15:06Z |
| format | Article |
| id | doaj.art-e7ce2d3db96e47fc9f4c19c3e8154e19 |
| institution | Directory Open Access Journal |
| issn | 2147-2688 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T11:15:06Z |
| publishDate | 2021-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-e7ce2d3db96e47fc9f4c19c3e8154e192023-02-15T16:18:55ZengGalenos YayineviHaseki Tıp Bülteni2147-26882147-26882021-03-0159213914410.4274/haseki.galenos.2021.679913049054Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature ReviewMelike Demir Caltekin0Ibrahim Caltekin1Taylan Onat2Demet Aydogan Kirmizi3Emre Baser4Serenat Eris Yalcin5Mustafa Kara6Ethem Serdar Yalvac7 Yozgat Bozok University Faculty of Medicine, Department of Obstetrics and Gynecology, Yozgat, Turkey Yozgat Bozok University Faculty of Medicine, Department of Emergency Medicine, Yozgat, Turkey Yozgat Bozok University Faculty of Medicine, Department of Obstetrics and Gynecology, Yozgat, Turkey Yozgat Bozok University Faculty of Medicine, Department of Obstetrics and Gynecology, Yozgat, Turkey Yozgat Bozok University Faculty of Medicine, Department of Obstetrics and Gynecology, Yozgat, Turkey University of Health Sciences Turkey, Antalya Training and Research Hospital, Clinic of Obstetrics and Gynecology, Antalya, Turkey Kırsehir Ahi Evran University Faculty of Medicine, Department of Obstetrics and Gynecology, Kırsehir, Turkey Yozgat Bozok University Faculty of Medicine, Department of Obstetrics and Gynecology, Yozgat, Turkey Aim:To evaluate subclinical inflammatory markers in hyperemesis gravidarum (HEG) cases and to determine the relationship of these markers with the gestational age at delivery and birth weight in pregnant women with HEG.Methods:Fifty-two patients who presented to our hospital between 1 May 2017 and 1 September 2019 with HEG and 60 pregnant women as the control group were included in this retrospectively designed study. The relationship of subclinical inflammatory markers such as the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the lymphocyte-to-monocyte ratio (LMR) with HEG, and their relationship with birth week and birth weight in HEG cases were examined.Results:In HEG cases, NLR and PLR values were higher (p=0.006 and p=0.004, respectively), whereas LMR values were lower (p<0.001). In HEG cases, gestational age at delivery had a negative correlation with NLR and PLR and positive correlation with LMR (r=-0.567, p<0.001; r=-0.322, p=0.02, and r=0.279 p=0.045, respectively). In addition, NLR and PLR had negative correlations with birth weight (r=-0.582, p<0.001; r=-0.302, p=0.029, respectively).Conclusion:While NLR and PLR values increase in HEG cases, LMR value decreases. It has been determined that varying rates of subclinical inflammatory markers in HEG are associated with preterm birth week and low birth weight. http://www.hasekidergisi.com/archives/archive-detail/article-preview/can-subclinical-nflammatory-markers-predict-birth-/46905 hyperemesis gravidarumsubclinical inflammationbirth weight |
| spellingShingle | Melike Demir Caltekin Ibrahim Caltekin Taylan Onat Demet Aydogan Kirmizi Emre Baser Serenat Eris Yalcin Mustafa Kara Ethem Serdar Yalvac Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review Haseki Tıp Bülteni hyperemesis gravidarum subclinical inflammation birth weight |
| title | Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review |
| title_full | Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review |
| title_fullStr | Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review |
| title_full_unstemmed | Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review |
| title_short | Can Subclinical Inflammatory Markers Predict Birth Time and Birth Weight in Hyperemesis Gravidarum?: A Comparative Study and Comprehensive Current Literature Review |
| title_sort | can subclinical inflammatory markers predict birth time and birth weight in hyperemesis gravidarum a comparative study and comprehensive current literature review |
| topic | hyperemesis gravidarum subclinical inflammation birth weight |
| url |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/can-subclinical-nflammatory-markers-predict-birth-/46905
|
| work_keys_str_mv | AT melikedemircaltekin cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT ibrahimcaltekin cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT taylanonat cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT demetaydogankirmizi cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT emrebaser cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT serenaterisyalcin cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT mustafakara cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview AT ethemserdaryalvac cansubclinicalinflammatorymarkerspredictbirthtimeandbirthweightinhyperemesisgravidarumacomparativestudyandcomprehensivecurrentliteraturereview |