TLR-2 Signaling Promotes IL-17A Production in CD4+CD25+Foxp3+ Regulatory Cells during Oropharyngeal Candidiasis

TLR-2 Signaling Promotes IL-17A Production in CD4+CD25+Foxp3+ Regulatory Cells during Oropharyngeal Candidiasis

Recent studies show that CD4+CD25+Foxp3+ regulatory cells (Tregs) produce effector cytokines under inflammatory conditions. However, the direct role of microbial agents that serve as toll-like receptor (TLR) ligands in the induction of effector cytokines in Tregs is less clear. Here we show that CD4...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Natarajan Bhaskaran, Samuel Cohen, Yifan Zhang, Aaron Weinberg, Pushpa Pandiyan
Format:	Artikel
Sprache:	English
Veröffentlicht:	MDPI AG 2015-03-01
Schriftenreihe:	Pathogens
Schlagworte:	Treg Foxp3 Th17 IL-17A TLR ligands TLR-2 Candida albicans IBD
Online Zugang:	http://www.mdpi.com/2076-0817/4/1/90

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