The diagnostic value of RDW in appendicitis

Introduction: Diagnosis of acute appendicitis is based on clinical manifestation .Some patients have atypical clinical symptoms, and diagnosis is difficult. Red blood cell distribution width (RDW) is a measure of heterogeneity in the size of circulating red blood cells. The aim of this study was to...

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Main Authors: Mahboub Pouraghaei, Payman Moharamzadeh, Hadi Khoshakhlagh, Yaghoub Asheghvatan
Format: Article
Language:English
Published: Tabriz University of Medical Sciences Press 2023-05-01
Series:Journal of Research in Clinical Medicine
Subjects:
Online Access:https://jrcm.tbzmed.ac.ir/PDF/jrcm-11-11.pdf
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author Mahboub Pouraghaei
Payman Moharamzadeh
Hadi Khoshakhlagh
Yaghoub Asheghvatan
author_facet Mahboub Pouraghaei
Payman Moharamzadeh
Hadi Khoshakhlagh
Yaghoub Asheghvatan
author_sort Mahboub Pouraghaei
collection DOAJ
description Introduction: Diagnosis of acute appendicitis is based on clinical manifestation .Some patients have atypical clinical symptoms, and diagnosis is difficult. Red blood cell distribution width (RDW) is a measure of heterogeneity in the size of circulating red blood cells. The aim of this study was to evaluate RDW values in diagnosis of appendicitis. Methods: This is a retrospective case-control study, in which 399 patients with pathological diagnosis of appendicitis were divided into two groups of acute appendicitis and complicated appendicitis and compared with 400 healthy controls for appendicitis. RDW, white blood cell (WBC), platelet count (PLT), and hemoglobin changes were compared in three groups of patients. Results: In all three groups, the ratio of men was significantly higher than women (P<0.05). WBC (P=0.00), PLT (P=0.01), and RDW (P=0.01) had a significant difference between the three groups. However, there was no significant difference in the hemoglobin level between the three groups (P=0.3). RDW level was significantly higher in complicated appendicitis compared to acute (P=0.09) and control group (P=0.012). Conclusion: The results of this study showed that RDW value in three groups were significantly different. However, these values are not clinically useful for detecting appendicitis due to the slow progression of RDW value in patients.
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spelling doaj.art-e7d3e4666d6b447ea4a1e56f37b1ce172023-05-27T09:00:13ZengTabriz University of Medical Sciences PressJournal of Research in Clinical Medicine2717-06162023-05-01111111110.34172/jrcm.2023.32102jrcm-32102The diagnostic value of RDW in appendicitisMahboub Pouraghaei0Payman Moharamzadeh1Hadi Khoshakhlagh2Yaghoub Asheghvatan3Emergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranEmergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranStudent Research Committee, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranEmergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranIntroduction: Diagnosis of acute appendicitis is based on clinical manifestation .Some patients have atypical clinical symptoms, and diagnosis is difficult. Red blood cell distribution width (RDW) is a measure of heterogeneity in the size of circulating red blood cells. The aim of this study was to evaluate RDW values in diagnosis of appendicitis. Methods: This is a retrospective case-control study, in which 399 patients with pathological diagnosis of appendicitis were divided into two groups of acute appendicitis and complicated appendicitis and compared with 400 healthy controls for appendicitis. RDW, white blood cell (WBC), platelet count (PLT), and hemoglobin changes were compared in three groups of patients. Results: In all three groups, the ratio of men was significantly higher than women (P<0.05). WBC (P=0.00), PLT (P=0.01), and RDW (P=0.01) had a significant difference between the three groups. However, there was no significant difference in the hemoglobin level between the three groups (P=0.3). RDW level was significantly higher in complicated appendicitis compared to acute (P=0.09) and control group (P=0.012). Conclusion: The results of this study showed that RDW value in three groups were significantly different. However, these values are not clinically useful for detecting appendicitis due to the slow progression of RDW value in patients.https://jrcm.tbzmed.ac.ir/PDF/jrcm-11-11.pdfappendixacute appendicitisrdwred blood cell
spellingShingle Mahboub Pouraghaei
Payman Moharamzadeh
Hadi Khoshakhlagh
Yaghoub Asheghvatan
The diagnostic value of RDW in appendicitis
Journal of Research in Clinical Medicine
appendix
acute appendicitis
rdw
red blood cell
title The diagnostic value of RDW in appendicitis
title_full The diagnostic value of RDW in appendicitis
title_fullStr The diagnostic value of RDW in appendicitis
title_full_unstemmed The diagnostic value of RDW in appendicitis
title_short The diagnostic value of RDW in appendicitis
title_sort diagnostic value of rdw in appendicitis
topic appendix
acute appendicitis
rdw
red blood cell
url https://jrcm.tbzmed.ac.ir/PDF/jrcm-11-11.pdf
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