The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer
Endometrial cancer is one of the most common cancers in developing and developed countries. Although the detection of this cancer is high at the early stages, there is still a lack of markers to monitor the disease, its recurrence, and metastasis. MiRNAs are in charge of the post-transcriptional reg...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/14/11489 |
| _version_ | 1797589073254154240 |
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| author | Anna Bogaczyk Izabela Zawlik Tomasz Zuzak Marta Kluz Natalia Potocka Tomasz Kluz |
| author_facet | Anna Bogaczyk Izabela Zawlik Tomasz Zuzak Marta Kluz Natalia Potocka Tomasz Kluz |
| author_sort | Anna Bogaczyk |
| collection | DOAJ |
| description | Endometrial cancer is one of the most common cancers in developing and developed countries. Although the detection of this cancer is high at the early stages, there is still a lack of markers to monitor the disease, its recurrence, and metastasis. MiRNAs are in charge of the post-transcriptional regulation of genes responsible for the most important biological processes, which is why they are increasingly used as biomarkers in many types of cancer. Many studies have demonstrated the influence of miRNAs on the processes related to carcinogenesis. The characteristics of miRNA expression profiles in endometrial cancer will allow their use as diagnostic and prognostic biomarkers. This paper focuses on the discussion of selected miRNAs based on the literature and their role in the development of endometrial cancer. |
| first_indexed | 2024-03-11T01:01:10Z |
| format | Article |
| id | doaj.art-e7d4beb121a441709806a8f34374bd17 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T01:01:10Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-e7d4beb121a441709806a8f34374bd172023-11-18T19:40:16ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-07-0124141148910.3390/ijms241411489The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial CancerAnna Bogaczyk0Izabela Zawlik1Tomasz Zuzak2Marta Kluz3Natalia Potocka4Tomasz Kluz5Department of Gynecology, Gynecology Oncology and Obstetrics, Fryderyk Chopin University Hospital, F.Szopena 2, 35-055 Rzeszow, PolandLaboratory of Molecular Biology, Centre for Innovative Research in Medical and Natural Sciences, Medical College of Rzeszow University, Warzywna 1a, 35-959 Rzeszow, PolandDepartment of Gynecology, Gynecology Oncology and Obstetrics, Fryderyk Chopin University Hospital, F.Szopena 2, 35-055 Rzeszow, PolandDepartment of Pathology, Fryderyk Chopin University Hospital, F.Szopena 2, 35-055 Rzeszow, PolandLaboratory of Molecular Biology, Centre for Innovative Research in Medical and Natural Sciences, Medical College of Rzeszow University, Warzywna 1a, 35-959 Rzeszow, PolandDepartment of Gynecology, Gynecology Oncology and Obstetrics, Fryderyk Chopin University Hospital, F.Szopena 2, 35-055 Rzeszow, PolandEndometrial cancer is one of the most common cancers in developing and developed countries. Although the detection of this cancer is high at the early stages, there is still a lack of markers to monitor the disease, its recurrence, and metastasis. MiRNAs are in charge of the post-transcriptional regulation of genes responsible for the most important biological processes, which is why they are increasingly used as biomarkers in many types of cancer. Many studies have demonstrated the influence of miRNAs on the processes related to carcinogenesis. The characteristics of miRNA expression profiles in endometrial cancer will allow their use as diagnostic and prognostic biomarkers. This paper focuses on the discussion of selected miRNAs based on the literature and their role in the development of endometrial cancer.https://www.mdpi.com/1422-0067/24/14/11489miRNAendometrial cancerepigeneticscarcinogenesis |
| spellingShingle | Anna Bogaczyk Izabela Zawlik Tomasz Zuzak Marta Kluz Natalia Potocka Tomasz Kluz The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer International Journal of Molecular Sciences miRNA endometrial cancer epigenetics carcinogenesis |
| title | The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer |
| title_full | The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer |
| title_fullStr | The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer |
| title_full_unstemmed | The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer |
| title_short | The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer |
| title_sort | role of mirnas in the development proliferation and progression of endometrial cancer |
| topic | miRNA endometrial cancer epigenetics carcinogenesis |
| url | https://www.mdpi.com/1422-0067/24/14/11489 |
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