Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two method...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Endocrinology Research Centre
2012-12-01
|
| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5540 |
| _version_ | 1826588140289130496 |
|---|---|
| author | Tatiana Vladimirovna Saprina Ekaterina Sergeevna Timokhina Irina Nikolaevna Vorozhtsova |
| author_facet | Tatiana Vladimirovna Saprina Ekaterina Sergeevna Timokhina Irina Nikolaevna Vorozhtsova |
| author_sort | Tatiana Vladimirovna Saprina |
| collection | DOAJ |
| description | Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two methods: oral glucose tolerance test with 75 g of glucose and glycated hemoglobin test. Results. HbA1c test with direct immunoturbidimetry is a highly sensitive method for diagnosis of glycemic disorders of pregnancy, provided that cut-off level is lowered to 5.5%. Conclusion. Mild anemia was not found to have a significant impact on diagnostic value of HbA1c test. |
| first_indexed | 2024-03-08T15:21:51Z |
| format | Article |
| id | doaj.art-e7d538f343164c31b541f2012b571a09 |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2025-03-14T16:36:36Z |
| publishDate | 2012-12-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-e7d538f343164c31b541f2012b571a092025-02-21T09:29:31ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782012-12-01154636810.14341/2072-0351-55405498Glycated hemoglobin test: diagnostic difficulties in gestational diabetesTatiana Vladimirovna Saprina0Ekaterina Sergeevna Timokhina1Irina Nikolaevna Vorozhtsova2Siberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityAims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two methods: oral glucose tolerance test with 75 g of glucose and glycated hemoglobin test. Results. HbA1c test with direct immunoturbidimetry is a highly sensitive method for diagnosis of glycemic disorders of pregnancy, provided that cut-off level is lowered to 5.5%. Conclusion. Mild anemia was not found to have a significant impact on diagnostic value of HbA1c test.https://www.dia-endojournals.ru/jour/article/view/5540pregnancygestational diabetesglycated hemoglobinsensitivityspecificity |
| spellingShingle | Tatiana Vladimirovna Saprina Ekaterina Sergeevna Timokhina Irina Nikolaevna Vorozhtsova Glycated hemoglobin test: diagnostic difficulties in gestational diabetes Сахарный диабет pregnancy gestational diabetes glycated hemoglobin sensitivity specificity |
| title | Glycated hemoglobin test: diagnostic difficulties in gestational diabetes |
| title_full | Glycated hemoglobin test: diagnostic difficulties in gestational diabetes |
| title_fullStr | Glycated hemoglobin test: diagnostic difficulties in gestational diabetes |
| title_full_unstemmed | Glycated hemoglobin test: diagnostic difficulties in gestational diabetes |
| title_short | Glycated hemoglobin test: diagnostic difficulties in gestational diabetes |
| title_sort | glycated hemoglobin test diagnostic difficulties in gestational diabetes |
| topic | pregnancy gestational diabetes glycated hemoglobin sensitivity specificity |
| url | https://www.dia-endojournals.ru/jour/article/view/5540 |
| work_keys_str_mv | AT tatianavladimirovnasaprina glycatedhemoglobintestdiagnosticdifficultiesingestationaldiabetes AT ekaterinasergeevnatimokhina glycatedhemoglobintestdiagnosticdifficultiesingestationaldiabetes AT irinanikolaevnavorozhtsova glycatedhemoglobintestdiagnosticdifficultiesingestationaldiabetes |