Application of electrophysiological measures in degenerative cervical myelopathy
Degenerative cervical myelopathy (DCM) is one of the leading causes of progressive spinal cord dysfunction in the elderly. Early diagnosis and treatment of DCM are essential to avoid permanent disability. The pathophysiology of DCM includes chronic ischemia, destruction of the blood–spinal cord barr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2022.834668/full |
| _version_ | 1818504252104900608 |
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| author | Zhengran Yu Zhengran Yu Wenxu Pan Jiacheng Chen Xinsheng Peng Zemin Ling Xuenong Zou |
| author_facet | Zhengran Yu Zhengran Yu Wenxu Pan Jiacheng Chen Xinsheng Peng Zemin Ling Xuenong Zou |
| author_sort | Zhengran Yu |
| collection | DOAJ |
| description | Degenerative cervical myelopathy (DCM) is one of the leading causes of progressive spinal cord dysfunction in the elderly. Early diagnosis and treatment of DCM are essential to avoid permanent disability. The pathophysiology of DCM includes chronic ischemia, destruction of the blood–spinal cord barrier, demyelination, and neuronal apoptosis. Electrophysiological studies including electromyography (EMG), nerve conduction study (NCS), motor evoked potentials (MEPs) and somatosensory evoked potentials (SEPs) are useful in detecting the presymptomatic pathological changes of the spinal cord, and thus supplementing the early clinical and radiographic examinations in the management of DCM. Preoperatively, they are helpful in detecting DCM and ruling out other diseases, assessing the spinal cord compression level and severity, predicting short- and long-term prognosis, and thus deciding the treatment methods. Intra- and postoperatively, they are also useful in monitoring neurological function change during surgeries and disease progression during follow-up rehabilitation. Here, we reviewed articles from 1979 to 2021, and tried to provide a comprehensive, evidence-based review of electrophysiological examinations in DCM. With this review, we aim to equip spinal surgeons with the basic knowledge to diagnosis and treat DCM using ancillary electrophysiological tests. |
| first_indexed | 2024-12-10T21:34:43Z |
| format | Article |
| id | doaj.art-e7d5c9e63d03414e8c27934ae25749dd |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-10T21:34:43Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-e7d5c9e63d03414e8c27934ae25749dd2022-12-22T01:32:41ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2022-08-011010.3389/fcell.2022.834668834668Application of electrophysiological measures in degenerative cervical myelopathyZhengran Yu0Zhengran Yu1Wenxu Pan2Jiacheng Chen3Xinsheng Peng4Zemin Ling5Xuenong Zou6Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Spine Surgery, Orthopedics Center of Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences, Guangzhou, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, Jinan University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Department of Spine Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDegenerative cervical myelopathy (DCM) is one of the leading causes of progressive spinal cord dysfunction in the elderly. Early diagnosis and treatment of DCM are essential to avoid permanent disability. The pathophysiology of DCM includes chronic ischemia, destruction of the blood–spinal cord barrier, demyelination, and neuronal apoptosis. Electrophysiological studies including electromyography (EMG), nerve conduction study (NCS), motor evoked potentials (MEPs) and somatosensory evoked potentials (SEPs) are useful in detecting the presymptomatic pathological changes of the spinal cord, and thus supplementing the early clinical and radiographic examinations in the management of DCM. Preoperatively, they are helpful in detecting DCM and ruling out other diseases, assessing the spinal cord compression level and severity, predicting short- and long-term prognosis, and thus deciding the treatment methods. Intra- and postoperatively, they are also useful in monitoring neurological function change during surgeries and disease progression during follow-up rehabilitation. Here, we reviewed articles from 1979 to 2021, and tried to provide a comprehensive, evidence-based review of electrophysiological examinations in DCM. With this review, we aim to equip spinal surgeons with the basic knowledge to diagnosis and treat DCM using ancillary electrophysiological tests.https://www.frontiersin.org/articles/10.3389/fcell.2022.834668/fulldegenerative cervical myelopathy (DCM)electrophysiological studiespreoperative assessmentintraoperative monitoring (IOM)postoperative evaluation |
| spellingShingle | Zhengran Yu Zhengran Yu Wenxu Pan Jiacheng Chen Xinsheng Peng Zemin Ling Xuenong Zou Application of electrophysiological measures in degenerative cervical myelopathy Frontiers in Cell and Developmental Biology degenerative cervical myelopathy (DCM) electrophysiological studies preoperative assessment intraoperative monitoring (IOM) postoperative evaluation |
| title | Application of electrophysiological measures in degenerative cervical myelopathy |
| title_full | Application of electrophysiological measures in degenerative cervical myelopathy |
| title_fullStr | Application of electrophysiological measures in degenerative cervical myelopathy |
| title_full_unstemmed | Application of electrophysiological measures in degenerative cervical myelopathy |
| title_short | Application of electrophysiological measures in degenerative cervical myelopathy |
| title_sort | application of electrophysiological measures in degenerative cervical myelopathy |
| topic | degenerative cervical myelopathy (DCM) electrophysiological studies preoperative assessment intraoperative monitoring (IOM) postoperative evaluation |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2022.834668/full |
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