Soluble egg antigen of Schistosoma japonicum induces pyroptosis in hepatic stellate cells by modulating ROS production

Soluble egg antigen of Schistosoma japonicum induces pyroptosis in hepatic stellate cells by modulating ROS production

Abstract Background Inflammation-induced dysfunction of hepatic stellate cells (HSCs) is involved in schistosomiasis-associated liver fibrosis, and soluble egg antigen (SEA) is a crucial pathogen-associated molecular pattern associated with liver injury in schistosomiasis. In addition, numerous stud...

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Bibliographic Details
Main Authors: De-Long Kong, Fan-Yun Kong, Xiang-Ye Liu, Chao Yan, Jie Cui, Ren-Xian Tang, Kui-Yang Zheng
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Parasites & Vectors
Subjects:
Schistosomiasis
Liver fibrosis
Pyroptosis
ROS
Online Access:http://link.springer.com/article/10.1186/s13071-019-3729-8

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