Psychiatric comorbidity and psycho-emotional status of patients with acne

Acne is a very common skin disease that has a significant impact on the psycho-emotional status of patients. This disease affects various areas of patients’ lives, leading to problems in body image, socialization, and sexuality. The change in appearance and the psycho-emotional stress associated wit...

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Main Authors: E. V. Dvoriankova, N. A. Shevchenko, O. V. Zhukova
Format: Article
Language:Russian
Published: Remedium Group LLC 2022-08-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/7008
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author E. V. Dvoriankova
N. A. Shevchenko
O. V. Zhukova
author_facet E. V. Dvoriankova
N. A. Shevchenko
O. V. Zhukova
author_sort E. V. Dvoriankova
collection DOAJ
description Acne is a very common skin disease that has a significant impact on the psycho-emotional status of patients. This disease affects various areas of patients’ lives, leading to problems in body image, socialization, and sexuality. The change in appearance and the psycho-emotional stress associated with the development of acne can also affect other aspects of  patients’ lives, including educational attainment, social activity, and a decline in academic performance and ability to work. Interpersonal problems in acne patients can occur not only with acquaintances and colleagues, but also within the family. The presence of  a  pronounced cosmetic defect, along with acute psycho-emotional problems, leads to a sharp decrease in quality of life, which is often exacerbated by comorbid psychiatric pathology: anxiety, depression, dysmorphophobia, self-injurious behavior, which certainly requires timely, effective and safe therapy for the underlying skin disease. Isotretinoin is an effective medication for the treatment of severe and treatment-resistant forms of acne. This drug has an  effect on all four pathophysiological factors of acne development. Isotretinoin reduces sebum production, regulates hyperkeratosis in the estuaries of sebaceous follicles, reduces the number of Propionibacterium acnes on the skin and is thought to have certain immunological and  anti-inflammatory effects. This is why the introduction of this drug into clinical practice has been recognized as an incredible triumph in the treatment of vulgar acne. However, the presence of  some undesirable side effects may limit its widespread use. In 1982, for example, the FDA issued a warning about the possible risk of depression and the occurrence of suicidal thoughts and attempts while using isotretinoin. However, this warning was not subsequently confirmed.
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spelling doaj.art-e7d6b58ecbf8492097136c54f33836142023-04-23T06:57:04ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902022-08-01013384610.21518/2079-701X-2022-16-13-38-466272Psychiatric comorbidity and psycho-emotional status of patients with acneE. V. Dvoriankova0N. A. Shevchenko1O. V. Zhukova2Center for Theoretical Problems of Physico-Chemical Pharmacology of the Russian Academy of Sciences; Medical Family Center “Pangea”Center for Сomprehensive Rehabilitation of Disabled People “Butovo”Peoples’ Friendship University of Russia; Moscow Scientific and Practical Center of Dermatovenereology and CosmetologyAcne is a very common skin disease that has a significant impact on the psycho-emotional status of patients. This disease affects various areas of patients’ lives, leading to problems in body image, socialization, and sexuality. The change in appearance and the psycho-emotional stress associated with the development of acne can also affect other aspects of  patients’ lives, including educational attainment, social activity, and a decline in academic performance and ability to work. Interpersonal problems in acne patients can occur not only with acquaintances and colleagues, but also within the family. The presence of  a  pronounced cosmetic defect, along with acute psycho-emotional problems, leads to a sharp decrease in quality of life, which is often exacerbated by comorbid psychiatric pathology: anxiety, depression, dysmorphophobia, self-injurious behavior, which certainly requires timely, effective and safe therapy for the underlying skin disease. Isotretinoin is an effective medication for the treatment of severe and treatment-resistant forms of acne. This drug has an  effect on all four pathophysiological factors of acne development. Isotretinoin reduces sebum production, regulates hyperkeratosis in the estuaries of sebaceous follicles, reduces the number of Propionibacterium acnes on the skin and is thought to have certain immunological and  anti-inflammatory effects. This is why the introduction of this drug into clinical practice has been recognized as an incredible triumph in the treatment of vulgar acne. However, the presence of  some undesirable side effects may limit its widespread use. In 1982, for example, the FDA issued a warning about the possible risk of depression and the occurrence of suicidal thoughts and attempts while using isotretinoin. However, this warning was not subsequently confirmed.https://www.med-sovet.pro/jour/article/view/7008acneanxietydepressionquality of lifeisotretinoin
spellingShingle E. V. Dvoriankova
N. A. Shevchenko
O. V. Zhukova
Psychiatric comorbidity and psycho-emotional status of patients with acne
Медицинский совет
acne
anxiety
depression
quality of life
isotretinoin
title Psychiatric comorbidity and psycho-emotional status of patients with acne
title_full Psychiatric comorbidity and psycho-emotional status of patients with acne
title_fullStr Psychiatric comorbidity and psycho-emotional status of patients with acne
title_full_unstemmed Psychiatric comorbidity and psycho-emotional status of patients with acne
title_short Psychiatric comorbidity and psycho-emotional status of patients with acne
title_sort psychiatric comorbidity and psycho emotional status of patients with acne
topic acne
anxiety
depression
quality of life
isotretinoin
url https://www.med-sovet.pro/jour/article/view/7008
work_keys_str_mv AT evdvoriankova psychiatriccomorbidityandpsychoemotionalstatusofpatientswithacne
AT nashevchenko psychiatriccomorbidityandpsychoemotionalstatusofpatientswithacne
AT ovzhukova psychiatriccomorbidityandpsychoemotionalstatusofpatientswithacne