Shaping Polarization Of Tumor-Associated Macrophages In Cancer Immunotherapy

Shaping Polarization Of Tumor-Associated Macrophages In Cancer Immunotherapy

Different stimuli can polarize macrophages into two basic types, M1 and M2. Tumor-associated macrophages (TAMs) in the tumor microenvironment (TME) are composed of heterogeneous subpopulations, which include the M1 anti-tumor and M2 pro-tumor phenotypes. TAMs predominantly play a M2-like tumor-promo...

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Bibliographic Details
Main Authors: Jing Gao, Yuanzheng Liang, Liang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
tumor-associated macrophages
polarization
tumor microenvironment
signaling pathways
cancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.888713/full

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