Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.

Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-κB-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger glucocorticoid response element-regulated gene expressi...

Detaylı Bibliyografya
Asıl Yazarlar:	Ilse M Beck, Zuzanna J Drebert, Ruben Hoya-Arias, Ali A Bahar, Michael Devos, Dorien Clarisse, Sofie Desmet, Nadia Bougarne, Bart Ruttens, Valerie Gossye, Geertrui Denecker, Sam Lievens, Marc Bracke, Jan Tavernier, Wim Declercq, Kris Gevaert, Wim Vanden Berghe, Guy Haegeman, Karolien De Bosscher
Materyal Türü:	Makale
Dil:	English
Baskı/Yayın Bilgisi:	Public Library of Science (PLoS) 2013-01-01
Seri Bilgileri:	PLoS ONE
Online Erişim:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23935933/?tool=EBI

Benzer Materyaller

How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer
Yazar:: Dorien Clarisse, ve diğerleri
Baskı/Yayın Bilgisi: (2021-08-01)

Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies.
Yazar:: Dorien Clarisse, ve diğerleri
Baskı/Yayın Bilgisi: (2018-01-01)

Improved Glucocorticoid Receptor Ligands: Fantastic Beasts, but How to Find Them?
Yazar:: Laura Van Moortel, ve diğerleri
Baskı/Yayın Bilgisi: (2020-09-01)

Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads
Yazar:: Chandra S. Chirumamilla, ve diğerleri
Baskı/Yayın Bilgisi: (2017-11-01)

Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor
Yazar:: Ioanna Petta, ve diğerleri
Baskı/Yayın Bilgisi: (2017-08-01)

PPARα in the Epigenetic Driver Seat of NAFLD: New Therapeutic Opportunities for Epigenetic Drugs?
Yazar:: Claudia Theys, ve diğerleri
Baskı/Yayın Bilgisi: (2022-11-01)

Live calcium and mitochondrial imaging in the enteric nervous system of Parkinson patients and controls
Yazar:: An-Sofie Desmet, ve diğerleri
Baskı/Yayın Bilgisi: (2017-08-01)

Deregulation of the Replisome Factor MCMBP Prompts Oncogenesis in Colorectal Carcinomas through Chromosomal Instability
Yazar:: Mauricio Quimbaya, ve diğerleri
Baskı/Yayın Bilgisi: (2014-09-01)

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
Yazar:: Katarzyna Szarc vel Szic, ve diğerleri
Baskı/Yayın Bilgisi: (2014-01-01)

Blood Surrogate Epigenetic Biomarkers of Atherosclerosis Reveal Common Signature of Inflamm-Aging-Disorders
Yazar:: Ken Declerck, ve diğerleri
Baskı/Yayın Bilgisi: (2019-06-01)

Tackling Chronic Inflammation with Withanolide Phytochemicals—A Withaferin A Perspective
Yazar:: Emilie Logie, ve diğerleri
Baskı/Yayın Bilgisi: (2020-11-01)

Characterization of Blood Surrogate Immune-Methylation Biomarkers for Immune Cell Infiltration in Chronic Inflammaging Disorders
Yazar:: Ken Declerck, ve diğerleri
Baskı/Yayın Bilgisi: (2019-11-01)

Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties
Yazar:: Kato Bredael, ve diğerleri
Baskı/Yayın Bilgisi: (2022-01-01)

Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ.
Yazar:: Nicolette Verhoog, ve diğerleri
Baskı/Yayın Bilgisi: (2014-01-01)

Molecular actions of PPARα in lipid metabolism and inflammation
Yazar:: Bougarne, N, ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Compound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment
Yazar:: S. J. Desmet, ve diğerleri
Baskı/Yayın Bilgisi: (2017-08-01)

Emerging immune and cell death mechanisms in stroke: Saponins as therapeutic candidates
Yazar:: Laura García-Pupo, ve diğerleri
Baskı/Yayın Bilgisi: (2020-12-01)

Sensor Selection and State Estimation for Unobservable and Non-Linear System Models
Yazar:: Thijs Devos, ve diğerleri
Baskı/Yayın Bilgisi: (2021-11-01)

Vehicle development, pharmacokinetics and toxicity of the anti-invasive agent 4-fluoro-3',4',5'-trimethoxychalcone in rodents.
Yazar:: Liselot M Mus, ve diğerleri
Baskı/Yayın Bilgisi: (2018-01-01)

Estimating Partnership Duration among MSM in Belgium—A Modeling Study
Yazar:: Achilleas Tsoumanis, ve diğerleri
Baskı/Yayın Bilgisi: (2024-05-01)

Contamination Sources and Transmission Routes for <i>Campylobacter</i> on (Mixed) Broiler Farms in Belgium, and Comparison of the Gut Microbiota of Flocks Colonized and Uncolonized with <i>Campylobacter</i>
Yazar:: Karolien Hertogs, ve diğerleri
Baskı/Yayın Bilgisi: (2021-01-01)

Chemical Composition of Essential Oils from Different Parts of <i>Zingiber</i> <i>kerrii</i> Craib and Their Antibacterial, Antioxidant, and Tyrosinase Inhibitory Activities
Yazar:: Aknarin Pintatum, ve diğerleri
Baskı/Yayın Bilgisi: (2020-02-01)

Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols
Yazar:: Gerlo Sarah, ve diğerleri
Baskı/Yayın Bilgisi: (2010-05-01)

“HLA-C: evolution, epigenetics, and pathological implications in the major histocompatibility complex”
Yazar:: Erick Velastegui, ve diğerleri
Baskı/Yayın Bilgisi: (2023-07-01)

Cytoglobin inhibits non-thermal plasma-induced apoptosis in melanoma cells through regulation of the NRF2-mediated antioxidant response
Yazar:: Joey De Backer, ve diğerleri
Baskı/Yayın Bilgisi: (2022-09-01)

Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network
Yazar:: Claudio D’Incal, ve diğerleri
Baskı/Yayın Bilgisi: (2022-04-01)

Crosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression
Yazar:: Sofie J. Desmet, ve diğerleri
Baskı/Yayın Bilgisi: (2024-06-01)

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)
Yazar:: Claudia Theys, ve diğerleri
Baskı/Yayın Bilgisi: (2024-01-01)

Violence de la jeunesse/violence sur la jeunesse : regards croisés sur la perception de la violence langagière de populations scolaires issues de l’immigration
Yazar:: Karolien Declercq, ve diğerleri
Baskı/Yayın Bilgisi: (2007-05-01)

How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines.
Yazar:: Ellen L Danneels, ve diğerleri
Baskı/Yayın Bilgisi: (2014-01-01)

Sparse Damage Detection with Complex Group Lasso and Adaptive Complex Group Lasso
Yazar:: Vasileios Dimopoulos, ve diğerleri
Baskı/Yayın Bilgisi: (2022-04-01)

Itineraries of enzymatically and non-enzymatically catalyzed substitutions at O-glycopyranosidic bonds
Yazar:: Wim Nerinckx, ve diğerleri
Baskı/Yayın Bilgisi: (2006-08-01)

PARTICIPATORY LANDSCAPE PLANNING: THE CASE OF THE “WESTVAARDERSPLASSEN” IN THE NETHERLANDS
Yazar:: Anouk GEVAERT, ve diğerleri
Baskı/Yayın Bilgisi: (2014-11-01)

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences
Yazar:: Ken Declerck, ve diğerleri
Baskı/Yayın Bilgisi: (2021-05-01)

New Tricks of Our Old Friend the Glucocorticoid Receptor
Yazar:: Dorien Clarisse, PhD, ve diğerleri
Baskı/Yayın Bilgisi: (2021-01-01)

Prevalence estimates of genital Chlamydia trachomatis infection in Belgium: results from two cross-sectional studies
Yazar:: Natalie Fischer, ve diğerleri
Baskı/Yayın Bilgisi: (2021-09-01)

La rebelión zapatista: productividad y resistencia culturales
Yazar:: Kristine Vanden Berghe
Baskı/Yayın Bilgisi: (2018-12-01)

The caracol and the beetle. A tension between ideology and form in the EZLN’s literary production
Yazar:: Kristine Vanden Berghe
Baskı/Yayın Bilgisi: (2018-12-01)

Idéologie et critique dans les récits zapatistes du Sous-commandant Marcos
Yazar:: Kristine Vanden Berghe
Baskı/Yayın Bilgisi: (2007-02-01)

Compte rendu de Segura (Maurice), La Faucille et le Condor. Le discours français sur l’Amérique latine (1950-1985)
Yazar:: Kristine Vanden Berghe
Baskı/Yayın Bilgisi: (2007-11-01)