Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.

Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein Hsp70 gene promoter activation.

Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-κB-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger glucocorticoid response element-regulated gene expressi...

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Những tác giả chính: Ilse M Beck, Zuzanna J Drebert, Ruben Hoya-Arias, Ali A Bahar, Michael Devos, Dorien Clarisse, Sofie Desmet, Nadia Bougarne, Bart Ruttens, Valerie Gossye, Geertrui Denecker, Sam Lievens, Marc Bracke, Jan Tavernier, Wim Declercq, Kris Gevaert, Wim Vanden Berghe, Guy Haegeman, Karolien De Bosscher
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Public Library of Science (PLoS) 2013-01-01
Loạt:PLoS ONE
Truy cập trực tuyến:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23935933/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23935933/?tool=EBI

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