PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE
Background. The distribution of sensitization among children and adolescence with allergic rhinitis (AR) and asthma and their impact on various allergic symptoms have been analyzed. Aim: investigate the distribution of sensitization among children with AR and asthma of the Ukrainian population....
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| Format: | Article |
| Language: | English |
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Bogomolets National Medical University
2023-03-01
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| Series: | Медична наука України |
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| Online Access: | https://msu-journal.com/index.php/journal/article/view/458 |
| _version_ | 1827805799116701696 |
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| author | O.V. Mozyrskaya |
| author_facet | O.V. Mozyrskaya |
| author_sort | O.V. Mozyrskaya |
| collection | DOAJ |
| description | Background. The distribution of sensitization among children and adolescence with allergic rhinitis (AR) and asthma and their impact on various allergic symptoms have been analyzed.
Aim: investigate the distribution of sensitization among children with AR and asthma of the Ukrainian population.
Material and methods. The study involved 280 children with AR and asthma aged 2–18 years. They were tested for sIgE on the most common allergens among Ukrainians - Dermatophagoides pteronyssinus, Dermatophagoides farinae, dog, cat, cockroach, birch (t03, Bet v1, Bet v2, Bet v4), plane tree, timothy (g06, Phl p1, Phl , Phl p6, Phl p7, Phl p12), ragweed, mugwort and Alternaria. Measurements of sIgE were performed by Western blotting according to the manufacturer's protocol (Simesta-Medivis, Ukraine-Germany).
Results. Among the sensitized subjects, 165 were sensitive to pollen allergens, sIgE was positive to birch in 64 subjects (22.5%), to mugwort ‒ 65 subjects (25.4%), ragweed ‒ 110 subjects (42.5%), timothy ‒ 69 subjects (24.6%), plane tree ‒ 12 subjects (5%). Positive sIgE to feline allergen was found in 114 (43.3%), dogs ‒ 77 (32.1%), Dermatophagoides pteronyssinus ‒ 66 (24.6%), Dermatophagoides farinae ‒ 32 (12%), Alternaria ‒ 38 (15 %), cockroaches ‒ 25 (10%).
Conclusions. Sensitization to airborne allergens is significantly associated with asthma and AR. The most important inhalant allergens consist of pollens (trees, grasses, and weeds), house dust mites, molds and animal dander. Among sensitive subjects to pollen allergens, allergy to ragweed was most spread. |
| first_indexed | 2024-03-11T21:31:20Z |
| format | Article |
| id | doaj.art-e7dbe9f945b54ce0b98e92879cbba883 |
| institution | Directory Open Access Journal |
| issn | 2664-472X 2664-4738 |
| language | English |
| last_indexed | 2024-03-11T21:31:20Z |
| publishDate | 2023-03-01 |
| publisher | Bogomolets National Medical University |
| record_format | Article |
| series | Медична наука України |
| spelling | doaj.art-e7dbe9f945b54ce0b98e92879cbba8832023-09-27T09:42:18ZengBogomolets National Medical UniversityМедична наука України2664-472X2664-47382023-03-01191121710.32345/2664-4738.1.2023.02458PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINEO.V. MozyrskayaBackground. The distribution of sensitization among children and adolescence with allergic rhinitis (AR) and asthma and their impact on various allergic symptoms have been analyzed. Aim: investigate the distribution of sensitization among children with AR and asthma of the Ukrainian population. Material and methods. The study involved 280 children with AR and asthma aged 2–18 years. They were tested for sIgE on the most common allergens among Ukrainians - Dermatophagoides pteronyssinus, Dermatophagoides farinae, dog, cat, cockroach, birch (t03, Bet v1, Bet v2, Bet v4), plane tree, timothy (g06, Phl p1, Phl , Phl p6, Phl p7, Phl p12), ragweed, mugwort and Alternaria. Measurements of sIgE were performed by Western blotting according to the manufacturer's protocol (Simesta-Medivis, Ukraine-Germany). Results. Among the sensitized subjects, 165 were sensitive to pollen allergens, sIgE was positive to birch in 64 subjects (22.5%), to mugwort ‒ 65 subjects (25.4%), ragweed ‒ 110 subjects (42.5%), timothy ‒ 69 subjects (24.6%), plane tree ‒ 12 subjects (5%). Positive sIgE to feline allergen was found in 114 (43.3%), dogs ‒ 77 (32.1%), Dermatophagoides pteronyssinus ‒ 66 (24.6%), Dermatophagoides farinae ‒ 32 (12%), Alternaria ‒ 38 (15 %), cockroaches ‒ 25 (10%). Conclusions. Sensitization to airborne allergens is significantly associated with asthma and AR. The most important inhalant allergens consist of pollens (trees, grasses, and weeds), house dust mites, molds and animal dander. Among sensitive subjects to pollen allergens, allergy to ragweed was most spread.https://msu-journal.com/index.php/journal/article/view/458allergic rhinitis, asthma, airborne allergens, sensitization |
| spellingShingle | O.V. Mozyrskaya PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE Медична наука України allergic rhinitis, asthma, airborne allergens, sensitization |
| title | PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE |
| title_full | PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE |
| title_fullStr | PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE |
| title_full_unstemmed | PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE |
| title_short | PREVALENCE OF SENSITIZATION TO AIRBORNE ALLERGENS IN PATIENTS WITH ALLERGIC RHINITIS AND ASTHMA IN UKRAINE |
| title_sort | prevalence of sensitization to airborne allergens in patients with allergic rhinitis and asthma in ukraine |
| topic | allergic rhinitis, asthma, airborne allergens, sensitization |
| url | https://msu-journal.com/index.php/journal/article/view/458 |
| work_keys_str_mv | AT ovmozyrskaya prevalenceofsensitizationtoairborneallergensinpatientswithallergicrhinitisandasthmainukraine |