Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports
Abstract Multiple myeloma (MM) is characterized by neoplastic proliferation of monoclonal antibody producing plasma cells. In clinical practice, pleural effusion is seen in up to 6% of MM patients, with many causative factors. Nevertheless, true myelomatous pleural effusion, defined as infiltration...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.1333 |
| _version_ | 1797242716018442240 |
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| author | Khai Lip Ng Sin Nee Tan Nai‐Chien Huan Mona Zaria Nasaruddin Noriah Othman Jamalul Azizi Abdul Rahaman |
| author_facet | Khai Lip Ng Sin Nee Tan Nai‐Chien Huan Mona Zaria Nasaruddin Noriah Othman Jamalul Azizi Abdul Rahaman |
| author_sort | Khai Lip Ng |
| collection | DOAJ |
| description | Abstract Multiple myeloma (MM) is characterized by neoplastic proliferation of monoclonal antibody producing plasma cells. In clinical practice, pleural effusion is seen in up to 6% of MM patients, with many causative factors. Nevertheless, true myelomatous pleural effusion, defined as infiltration of the pleura by myeloma cells, is very rare. In this case report, we present two patients with biopsy proven myelomatous pleural effusion. The first patient developed myelomatous pleural effusion as initial presentation while the second patient's pleural effusion occurred during disease relapse. In both cases, prompt diagnosis via medical thoracoscopy (MT) followed by early commencement of myeloma specific chemotherapy led to clinical, biochemical, and radiological resolution and therefore were crucial steps in the management of myelomatous pleural effusion. |
| first_indexed | 2024-04-24T18:43:38Z |
| format | Article |
| id | doaj.art-e7dcfc300fe048508a69d7bf2c8b6299 |
| institution | Directory Open Access Journal |
| issn | 2051-3380 |
| language | English |
| last_indexed | 2024-04-24T18:43:38Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj.art-e7dcfc300fe048508a69d7bf2c8b62992024-03-27T08:30:32ZengWileyRespirology Case Reports2051-33802024-03-01123n/an/a10.1002/rcr2.1333Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reportsKhai Lip Ng0Sin Nee Tan1Nai‐Chien Huan2Mona Zaria Nasaruddin3Noriah Othman4Jamalul Azizi Abdul Rahaman5Department of Medicine Melaka Hospital Melaka MalaysiaDepartment of Pulmonology Serdang Hospital Kajang MalaysiaDepartment of Respiratory Medicine Queen Elizabeth Hospital Kota Kinabalu MalaysiaDepartment of Pulmonology Serdang Hospital Kajang MalaysiaDepartment of Pathology Serdang Hospital Kajang MalaysiaDepartment of Pulmonology Serdang Hospital Kajang MalaysiaAbstract Multiple myeloma (MM) is characterized by neoplastic proliferation of monoclonal antibody producing plasma cells. In clinical practice, pleural effusion is seen in up to 6% of MM patients, with many causative factors. Nevertheless, true myelomatous pleural effusion, defined as infiltration of the pleura by myeloma cells, is very rare. In this case report, we present two patients with biopsy proven myelomatous pleural effusion. The first patient developed myelomatous pleural effusion as initial presentation while the second patient's pleural effusion occurred during disease relapse. In both cases, prompt diagnosis via medical thoracoscopy (MT) followed by early commencement of myeloma specific chemotherapy led to clinical, biochemical, and radiological resolution and therefore were crucial steps in the management of myelomatous pleural effusion.https://doi.org/10.1002/rcr2.1333medical thoracoscopymultiple myelomamyelomatous effusionpleural effusion |
| spellingShingle | Khai Lip Ng Sin Nee Tan Nai‐Chien Huan Mona Zaria Nasaruddin Noriah Othman Jamalul Azizi Abdul Rahaman Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports Respirology Case Reports medical thoracoscopy multiple myeloma myelomatous effusion pleural effusion |
| title | Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports |
| title_full | Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports |
| title_fullStr | Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports |
| title_full_unstemmed | Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports |
| title_short | Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports |
| title_sort | utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion 2 case reports |
| topic | medical thoracoscopy multiple myeloma myelomatous effusion pleural effusion |
| url | https://doi.org/10.1002/rcr2.1333 |
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