Recent Insight on Regulations of FBXW7 and Its Role in Immunotherapy

Recent Insight on Regulations of FBXW7 and Its Role in Immunotherapy

SCFFBXW7 E3 ubiquitin ligase complex is a crucial enzyme of the ubiquitin proteasome system that participates in variant activities of cell process, and its component FBXW7 (F-box and WD repeat domain–containing 7) is responsible for recognizing and binding to substrates. The expression of FBXW7 is...

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Bibliographic Details
Main Authors: Liangliang Xing, Leidi Xu, Yong Zhang, Yinggang Che, Min Wang, Yongxiang Shao, Dan Qiu, Honglian Yu, Feng Zhao, Jian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
FBXW7
ubiquitination
epigenetic regulation
immunity
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.925041/full

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