Age-Related Macular Degeneration: Classification and Pathogenesis
Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity. AMD is a neurodegenerative disease and is now the...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2014-12-01
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| Series: | Türk Oftalmoloji Dergisi |
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| Online Access: | http://www.oftalmoloji.org/article_7551/Age-related-Macular-Degeneration-Classification-And-Pathogenesis |
| Summary: | Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age
with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity. AMD is a
neurodegenerative disease and is now the most common cause of registrable blindness in the western world. The prevalence of the disease
is given as 10% in 65-75-year-old population and as 25% after 75 of age. AMD is a multi-faceted and complex condition. Although
different forms of AMD share some common underlying pathological features and causes, there are unique mechanisms for each form.
Effective therapies should be derived from in-depth knowledge about each subtype of AMD and should be tailored to address the specific
needs in each disease subtype. (Turk J Ophthalmol 2014; 44: 476-80) |
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| ISSN: | 1300-0659 2147-2661 |