Age-Related Macular Degeneration: Classification and Pathogenesis

Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity. AMD is a neurodegenerative disease and is now the...

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Main Author: İmren Akkoyun
Format: Article
Language:English
Published: Galenos Yayinevi 2014-12-01
Series:Türk Oftalmoloji Dergisi
Subjects:
Online Access:http://www.oftalmoloji.org/article_7551/Age-related-Macular-Degeneration-Classification-And-Pathogenesis
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author İmren Akkoyun
author_facet İmren Akkoyun
author_sort İmren Akkoyun
collection DOAJ
description Age-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity. AMD is a neurodegenerative disease and is now the most common cause of registrable blindness in the western world. The prevalence of the disease is given as 10% in 65-75-year-old population and as 25% after 75 of age. AMD is a multi-faceted and complex condition. Although different forms of AMD share some common underlying pathological features and causes, there are unique mechanisms for each form. Effective therapies should be derived from in-depth knowledge about each subtype of AMD and should be tailored to address the specific needs in each disease subtype. (Turk J Ophthalmol 2014; 44: 476-80)
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spelling doaj.art-e7e1a0261b5946a98651c21547b38ee42023-02-15T16:20:29ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612014-12-0144647648010.4274/tjo.80008Age-Related Macular Degeneration: Classification and Pathogenesisİmren Akkoyun0Başkent Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Ankara, TürkiyeAge-related macular degeneration (AMD) was first described in 1885 by Otto Haab as a disease in patients above 50 years of age with progressive retinal pigment epithelial and atrophic degenerations of the macula reducing the central visual acuity. AMD is a neurodegenerative disease and is now the most common cause of registrable blindness in the western world. The prevalence of the disease is given as 10% in 65-75-year-old population and as 25% after 75 of age. AMD is a multi-faceted and complex condition. Although different forms of AMD share some common underlying pathological features and causes, there are unique mechanisms for each form. Effective therapies should be derived from in-depth knowledge about each subtype of AMD and should be tailored to address the specific needs in each disease subtype. (Turk J Ophthalmol 2014; 44: 476-80)http://www.oftalmoloji.org/article_7551/Age-related-Macular-Degeneration-Classification-And-PathogenesisAMDgeographic atrophyneovascular AMDpathogenesis
spellingShingle İmren Akkoyun
Age-Related Macular Degeneration: Classification and Pathogenesis
Türk Oftalmoloji Dergisi
AMD
geographic atrophy
neovascular AMD
pathogenesis
title Age-Related Macular Degeneration: Classification and Pathogenesis
title_full Age-Related Macular Degeneration: Classification and Pathogenesis
title_fullStr Age-Related Macular Degeneration: Classification and Pathogenesis
title_full_unstemmed Age-Related Macular Degeneration: Classification and Pathogenesis
title_short Age-Related Macular Degeneration: Classification and Pathogenesis
title_sort age related macular degeneration classification and pathogenesis
topic AMD
geographic atrophy
neovascular AMD
pathogenesis
url http://www.oftalmoloji.org/article_7551/Age-related-Macular-Degeneration-Classification-And-Pathogenesis
work_keys_str_mv AT imrenakkoyun agerelatedmaculardegenerationclassificationandpathogenesis