Evaluation of single-sample network inference methods for precision oncology

Abstract A major challenge in precision oncology is to detect targetable cancer vulnerabilities in individual patients. Modeling high-throughput omics data in biological networks allows identifying key molecules and processes of tumorigenesis. Traditionally, network inference methods rely on many sa...

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Bibliographic Details
Main Authors: Joke Deschildre, Boris Vandemoortele, Jens Uwe Loers, Katleen De Preter, Vanessa Vermeirssen
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00340-w

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