Distinct regions within the GluN2C subunit regulate the surface delivery of NMDA receptors

Distinct regions within the GluN2C subunit regulate the surface delivery of NMDA receptors

N-methyl-D-aspartate (NMDA) receptors mediate fast excitatory synaptic transmission in the mammalian central nervous system. The activation of NMDA receptors plays a key role in brain development, synaptic plasticity, and memory formation, and is a major contributor to many neuropsychiatric disorder...

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Bibliographic Details
Main Authors: Katarina eLichnerova, Martina eKaniakova, Kristyna eSkrenkova, Ladislav eVyklicky, Martin eHorak
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Electrophysiology
ion channel
glutamate receptor
intracellular trafficking
cerebellar granule cells
endoplasmic reticulum.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00375/full

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