Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual

Human iPSC Line, ZZUNEUi001-A, was generated from a healthy 38-year-old male individual, using non-integrating reprogramming methods. The resulting iPSCs were integration-free, expressed pluripotency stem cell markers, exhibited the potential for tri-lineage differentiation both in vitro and vivo, a...

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Main Authors: Jiwei Zhang, Liting Wei, Rui Wang, Xunhua Li, Zhangsuo Liu
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301112
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author Jiwei Zhang
Liting Wei
Rui Wang
Xunhua Li
Zhangsuo Liu
author_facet Jiwei Zhang
Liting Wei
Rui Wang
Xunhua Li
Zhangsuo Liu
author_sort Jiwei Zhang
collection DOAJ
description Human iPSC Line, ZZUNEUi001-A, was generated from a healthy 38-year-old male individual, using non-integrating reprogramming methods. The resulting iPSCs were integration-free, expressed pluripotency stem cell markers, exhibited the potential for tri-lineage differentiation both in vitro and vivo, and maintained the normal karyotype. This cell line can be used as a control line for disease modelling.
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spelling doaj.art-e7e3bef58a264fb8a44e4c281c08da882022-12-22T01:34:00ZengElsevierStem Cell Research1873-50612020-05-0145Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individualJiwei Zhang0Liting Wei1Rui Wang2Xunhua Li3Zhangsuo Liu4The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, Henan, China; Corresponding authors.Department of Neurology, Luoyang Central Hospital affiliated to Zhengzhou University, Luoyang 467500, Henan, ChinaGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, Guangdong, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, Guangdong, ChinaThe First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, Henan, China; Corresponding authors.Human iPSC Line, ZZUNEUi001-A, was generated from a healthy 38-year-old male individual, using non-integrating reprogramming methods. The resulting iPSCs were integration-free, expressed pluripotency stem cell markers, exhibited the potential for tri-lineage differentiation both in vitro and vivo, and maintained the normal karyotype. This cell line can be used as a control line for disease modelling.http://www.sciencedirect.com/science/article/pii/S1873506120301112
spellingShingle Jiwei Zhang
Liting Wei
Rui Wang
Xunhua Li
Zhangsuo Liu
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
Stem Cell Research
title Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
title_full Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
title_fullStr Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
title_full_unstemmed Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
title_short Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual
title_sort generation of an integration free induced pluripotent stem cell ipsc line zzuneui001 a from a healthy male individual
url http://www.sciencedirect.com/science/article/pii/S1873506120301112
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