Single-cell Analysis Technologies for Immuno-oncology Research: from Mechanistic Delineation to Biomarker Discovery

Single-cell Analysis Technologies for Immuno-oncology Research: from Mechanistic Delineation to Biomarker Discovery

The successes with immune checkpoint blockade (ICB) and chimeric antigen receptor (CAR)-T-cell therapy in treating multiple cancer types have established immunotherapy as a powerful curative option for patients with advanced cancers. Unfortunately, many patients do not derive benefit or long-term re...

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Bibliographic Details
Main Authors: Zhiliang Bai, Graham Su, Rong Fan
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Single-cell analysis
Immunotherapy
Biomarker discovery
Checkpoint blockade
CAR-T
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022921000772

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