A case of placental site trophoblastic tumor managed in a low resource setting

Placental trophoblastic site tumor (PSTT) is a rare type of gestational trophoblastic neoplasia (GTN). PSTT has a higher mortality than other types of gestational trophoblastic disease (GTD), with a rate of 16.1%, due to its relatively unpredictable behavior and reduced response to chemotherapy. Its...

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Main Authors: Christophe Millien, Rebecca Henderson, Jean Joel Saint Hubert, Carlos Parra-Herran, Thomas Randall
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Gynecologic Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578924000080
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author Christophe Millien
Rebecca Henderson
Jean Joel Saint Hubert
Carlos Parra-Herran
Thomas Randall
author_facet Christophe Millien
Rebecca Henderson
Jean Joel Saint Hubert
Carlos Parra-Herran
Thomas Randall
author_sort Christophe Millien
collection DOAJ
description Placental trophoblastic site tumor (PSTT) is a rare type of gestational trophoblastic neoplasia (GTN). PSTT has a higher mortality than other types of gestational trophoblastic disease (GTD), with a rate of 16.1%, due to its relatively unpredictable behavior and reduced response to chemotherapy. Its diagnostic and management are very challenging in Low resources settings particularity in Haiti where MRI, PET Scan and IHC are not available. Further, the follow-up is very difficult because of social, political, and economic issues limiting the capacity of our patients to be present at all scheduled visits. No case of PSTT has been publicly described yet the Haitian experience in the literature in the management of such case compared to the developed world. We present a case of PSTT successfully diagnosed and managed at Mirebalais University Hospital (MUH) in Haiti with the support of telepathology and intentional partners while highlighting the difference that we observed compare to the developed world.
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spelling doaj.art-e7e9103ee3af4689802be860cd409d6e2024-02-21T05:28:50ZengElsevierGynecologic Oncology Reports2352-57892024-02-0151101329A case of placental site trophoblastic tumor managed in a low resource settingChristophe Millien0Rebecca Henderson1Jean Joel Saint Hubert2Carlos Parra-Herran3Thomas Randall4University Hospital of Mirebalais, Zanmi Lasante, Mirebalais, Haiti; Corresponding author.University of Florida College of Medicine, Gainesville, FL, USAUniversity Hospital of Mirebalais, Zanmi Lasante, Mirebalais, HaitiDepartment of Pathology, Brigham and Women’s Hospital, Boston, MA, USADepartment of Gynecologic Oncology, Massachusetts General Hospital, Boston, MA, USAPlacental trophoblastic site tumor (PSTT) is a rare type of gestational trophoblastic neoplasia (GTN). PSTT has a higher mortality than other types of gestational trophoblastic disease (GTD), with a rate of 16.1%, due to its relatively unpredictable behavior and reduced response to chemotherapy. Its diagnostic and management are very challenging in Low resources settings particularity in Haiti where MRI, PET Scan and IHC are not available. Further, the follow-up is very difficult because of social, political, and economic issues limiting the capacity of our patients to be present at all scheduled visits. No case of PSTT has been publicly described yet the Haitian experience in the literature in the management of such case compared to the developed world. We present a case of PSTT successfully diagnosed and managed at Mirebalais University Hospital (MUH) in Haiti with the support of telepathology and intentional partners while highlighting the difference that we observed compare to the developed world.http://www.sciencedirect.com/science/article/pii/S2352578924000080PSTTPlacental site trophoblastic tumorHaiti
spellingShingle Christophe Millien
Rebecca Henderson
Jean Joel Saint Hubert
Carlos Parra-Herran
Thomas Randall
A case of placental site trophoblastic tumor managed in a low resource setting
Gynecologic Oncology Reports
PSTT
Placental site trophoblastic tumor
Haiti
title A case of placental site trophoblastic tumor managed in a low resource setting
title_full A case of placental site trophoblastic tumor managed in a low resource setting
title_fullStr A case of placental site trophoblastic tumor managed in a low resource setting
title_full_unstemmed A case of placental site trophoblastic tumor managed in a low resource setting
title_short A case of placental site trophoblastic tumor managed in a low resource setting
title_sort case of placental site trophoblastic tumor managed in a low resource setting
topic PSTT
Placental site trophoblastic tumor
Haiti
url http://www.sciencedirect.com/science/article/pii/S2352578924000080
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