Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature

Albinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements wit...

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Main Authors: Chinedu Onwuka Ndukwe, Michael Emeka Chiemeka, Felix Emeka Menkiti, Florence Ifeoma Ezejiofor, Gerald Kenechi Ike, Titus O. Chukwuanukwu
Format: Article
Language:English
Published: Oman Medical Specialty Board 2022-09-01
Series:Oman Medical Journal
Subjects:
Online Access:https://omjournal.org/articleDetails.aspx?coType=1&aId=3246
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author Chinedu Onwuka Ndukwe
Michael Emeka Chiemeka
Felix Emeka Menkiti
Florence Ifeoma Ezejiofor
Gerald Kenechi Ike
Titus O. Chukwuanukwu
author_facet Chinedu Onwuka Ndukwe
Michael Emeka Chiemeka
Felix Emeka Menkiti
Florence Ifeoma Ezejiofor
Gerald Kenechi Ike
Titus O. Chukwuanukwu
author_sort Chinedu Onwuka Ndukwe
collection DOAJ
description Albinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements with an unclear histogenesis. To our knowledge, this has not been reported in an African albino. Here, we report the index case of this rare tumor in an albino of African descent.
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spelling doaj.art-e7ea209fcc874dad921c515d046d60472022-12-22T04:06:20ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042022-09-01375e417e41710.5001/omj.2022.07Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of LiteratureChinedu Onwuka Ndukwe0Michael Emeka Chiemeka1Felix Emeka Menkiti2Florence Ifeoma Ezejiofor3Gerald Kenechi Ike4Titus O. Chukwuanukwu5Department of Anatomic Pathology and Forensic Medicine, Faculty of Medicine, College of Health Sciences and Technology, Nnamdi Azikiwe University, Anambra State, NigeriaDepartment of Anatomic Pathology and Forensic Medicine, Faculty of Medicine, College of Health Sciences and Technology, Nnamdi Azikiwe University, Anambra State, NigeriaDepartment of Anatomic Pathology and Forensic Medicine, Faculty of Medicine, College of Health Sciences and Technology, Nnamdi Azikiwe University, Anambra State, NigeriaDepartment of Anatomic Pathology and Forensic Medicine, Faculty of Medicine, College of Health Sciences and Technology, Nnamdi Azikiwe University, Anambra State, NigeriaDepartment of Histopathology, Nnamdi Azikiwe University Teaching Hospital, Anambra State, NigeriaDepartment of Surgery, Faculty of Medicine, College of Health Sciences and Technology, Nnamdi Azikiwe University, Anambra State, NigeriaAlbinism results from a deficiency of the protein responsible for melanin production in melanocytes. Albinos are at an increased risk of dermatoses and malignancies. Primary carcinosarcoma of the skin is an exceedingly rare biphasic tumor composed of malignant epithelial and mesenchymal elements with an unclear histogenesis. To our knowledge, this has not been reported in an African albino. Here, we report the index case of this rare tumor in an albino of African descent.https://omjournal.org/articleDetails.aspx?coType=1&aId=3246albinismcarcinosarcomaimmunohistochemistryskin cancernigeria
spellingShingle Chinedu Onwuka Ndukwe
Michael Emeka Chiemeka
Felix Emeka Menkiti
Florence Ifeoma Ezejiofor
Gerald Kenechi Ike
Titus O. Chukwuanukwu
Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature
Oman Medical Journal
albinism
carcinosarcoma
immunohistochemistry
skin cancer
nigeria
title Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature
title_full Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature
title_fullStr Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature
title_full_unstemmed Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature
title_short Primary Carcinosarcoma of the Skin in an African Albino: Case Report and Review of Literature
title_sort primary carcinosarcoma of the skin in an african albino case report and review of literature
topic albinism
carcinosarcoma
immunohistochemistry
skin cancer
nigeria
url https://omjournal.org/articleDetails.aspx?coType=1&aId=3246
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