Crystal Breakage Due to Combined Normal and Shear Loading
Combined normal and shear stress on particles occurs in many devices for solid–liquid separation. Protein crystals are much more fragile compared to conventional crystals because of their high water content. Therefore, unwanted crystal breakage is to be expected in the processing of such materials....
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Crystals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4352/12/5/644 |
| _version_ | 1797500541273636864 |
|---|---|
| author | Benjamin Radel Marco Gleiß Hermann Nirschl |
| author_facet | Benjamin Radel Marco Gleiß Hermann Nirschl |
| author_sort | Benjamin Radel |
| collection | DOAJ |
| description | Combined normal and shear stress on particles occurs in many devices for solid–liquid separation. Protein crystals are much more fragile compared to conventional crystals because of their high water content. Therefore, unwanted crystal breakage is to be expected in the processing of such materials. The influence of pressure and shearing has been investigated individually in the past. To analyze the influence of combined shear and normal stress on protein crystals, a modified shear cell for a ring shear tester is used. This device allows one to accurately vary the normal and shear stress on moist crystals in a saturated particle bed. Analyzing the protein crystals in a moist state is important because the mechanical properties change significantly after drying. The results show a big influence of the applied normal stress on crystal breakage while shearing. Higher normal loading leads to a much bigger comminution. The shear velocity, however, has a comparatively negligible influence. |
| first_indexed | 2024-03-10T03:05:17Z |
| format | Article |
| id | doaj.art-e7eaafd1f5f24092a1610f783acdc594 |
| institution | Directory Open Access Journal |
| issn | 2073-4352 |
| language | English |
| last_indexed | 2024-03-10T03:05:17Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Crystals |
| spelling | doaj.art-e7eaafd1f5f24092a1610f783acdc5942023-11-23T10:34:53ZengMDPI AGCrystals2073-43522022-04-0112564410.3390/cryst12050644Crystal Breakage Due to Combined Normal and Shear LoadingBenjamin Radel0Marco Gleiß1Hermann Nirschl2Institute of Mechanical Process Engineering and Mechanics, Karlsruhe Institute of Technology, 8 Strasse am Forum, 76137 Karlsruhe, GermanyInstitute of Mechanical Process Engineering and Mechanics, Karlsruhe Institute of Technology, 8 Strasse am Forum, 76137 Karlsruhe, GermanyInstitute of Mechanical Process Engineering and Mechanics, Karlsruhe Institute of Technology, 8 Strasse am Forum, 76137 Karlsruhe, GermanyCombined normal and shear stress on particles occurs in many devices for solid–liquid separation. Protein crystals are much more fragile compared to conventional crystals because of their high water content. Therefore, unwanted crystal breakage is to be expected in the processing of such materials. The influence of pressure and shearing has been investigated individually in the past. To analyze the influence of combined shear and normal stress on protein crystals, a modified shear cell for a ring shear tester is used. This device allows one to accurately vary the normal and shear stress on moist crystals in a saturated particle bed. Analyzing the protein crystals in a moist state is important because the mechanical properties change significantly after drying. The results show a big influence of the applied normal stress on crystal breakage while shearing. Higher normal loading leads to a much bigger comminution. The shear velocity, however, has a comparatively negligible influence.https://www.mdpi.com/2073-4352/12/5/644protein crystalsbreakageshear stress |
| spellingShingle | Benjamin Radel Marco Gleiß Hermann Nirschl Crystal Breakage Due to Combined Normal and Shear Loading Crystals protein crystals breakage shear stress |
| title | Crystal Breakage Due to Combined Normal and Shear Loading |
| title_full | Crystal Breakage Due to Combined Normal and Shear Loading |
| title_fullStr | Crystal Breakage Due to Combined Normal and Shear Loading |
| title_full_unstemmed | Crystal Breakage Due to Combined Normal and Shear Loading |
| title_short | Crystal Breakage Due to Combined Normal and Shear Loading |
| title_sort | crystal breakage due to combined normal and shear loading |
| topic | protein crystals breakage shear stress |
| url | https://www.mdpi.com/2073-4352/12/5/644 |
| work_keys_str_mv | AT benjaminradel crystalbreakageduetocombinednormalandshearloading AT marcogleiß crystalbreakageduetocombinednormalandshearloading AT hermannnirschl crystalbreakageduetocombinednormalandshearloading |